Projects per year
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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FWOSB54: Improve the reprogramming of human adult skin-derived fibroblasts into functional hepatocytes by directed evolution of hepatocyte nuclear factors
Rombaut, M. (Mandate), De Kock, J. (Administrative Promotor) & Vanhaecke, T. (Co-Promotor)
1/01/19 → 31/12/23
Project: Fundamental
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Human stem cell-derived hepatic cells recapitulate polygenic risk in MASLD development and highlight CD36 as a key mediator
Gatzios, A., Stinckens, M., Verhoeven, A., Rombaut, M., De Win, D., Heymans, A., Loosen, A., Van Goethem, F., De Kock, J., Rodrigues, R., Boeckmans, J. & Vanhaecke, T., 13 Jul 2026, In: Life Sciences. 124587.Research output: Contribution to journal › Article › peer-review
Open Access -
A robust bacterial high-throughput screening assay to identify pharmacological chaperones targeting human homogentisate 1,2-dioxygenase missense variants in alkaptonuria
Lequeue, S., Allach, H., Nulmans, I., Desmet, L., Salvi, N. S., Rombaut, M., Neuckermans, J., Schwaneberg, U., Vanhaecke, T. & Kock, J. D., Oct 2025, In: European Journal of Pharmacology. 1005, 13 p., 178048.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Genetic predisposition for hepatic fat accumulation impacts the uptake of fatty acids through fatty acid translocase in a human stem cell-based in vitro model
Gatzios, A., Rombaut, M., De Kock, J., Verhoeven, A., De Win, D., Heymans, A., Rogiers, V., Rodrigues, R., Boeckmans, J. & Vanhaecke, T., May 2025, Abstract Book of EASL Congress 2025. Elsevier, Vol. 82(S1). p. S585-S586 2 p. FRI-338Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
Open Access -
Genetic predisposition for hepatic fat accumulation impacts the uptake of fatty acids through fatty acid translocase in a human stem cell-based in vitro model
Gatzios, A., Rombaut, M., De Kock, J., Verhoeven, A., De Win, D., Heymans, A., Rogiers, V., Rodrigues, R., Boeckmans, J. & Vanhaecke, T., 9 May 2025, (Unpublished). 1 p.Research output: Unpublished contribution to conference › Poster
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Hepatic profiling of forward programmed human skin-derived precursor cells using a multi-omics approach
Stinckens, M., Rombaut, M., Del'Haye, G., Gatzios, A., Kochzius, M., Rodrigues, R., Vanhaecke, T. & De Kock, J., 25 Sept 2025, (Unpublished).Research output: Unpublished contribution to conference › Poster
Prizes
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HepaSTAR: Hepatogenic programming of human skin-derived precursor cells and their evaluation for liver disease therapy and regeneration.
Rombaut, M. (Recipient), 2020
Prize: Other distinction
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Preclinical development of a human relevant in vitro model to study HGD mRNA therapy in alkaptonuria
Rombaut, M. (Recipient), 12 Dec 2023
Prize: Other distinction
Activities
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BeSSCR 2025
Rombaut, M. (Visitor)
28 Nov 2025Activity: Participating in or organising an event › Participation in conference
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Unraveling the metabolic landscape of alkaptonuria through an in vitro liver disease model
Rombaut, M. (Speaker)
22 Oct 2025Activity: Talk or presentation › Talk or presentation at a conference
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Genetic predisposition for anti-MASH drug response: a population-based in vitro study
Gatzios, A. (Speaker), Rombaut, M. (Contributor), De Kock, J. (Contributor), De Win, D. (Contributor), Heymans, A. (Contributor), Rogiers, V. (Contributor), Marcelino Rodrigues, R. (Contributor), Boeckmans, J. (Contributor) & Vanhaecke, T. (Contributor)
5 Jun 2024Activity: Talk or presentation › Talk or presentation at a conference
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7th IC-3Rs Symposium
Rombaut, M. (Participant)
19 Sept 2024Activity: Participating in or organising an event › Participation in conference
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Genetic predisposition for anti-MASH drug response: a population-based in vitro study
Gatzios, A. (Speaker), Rombaut, M. (Contributor), De Kock, J. (Contributor), De Win, D. (Contributor), Heymans, A. (Contributor), Rogiers, V. (Contributor), Marcelino Rodrigues, R. (Contributor), Boeckmans, J. (Contributor) & Vanhaecke, T. (Contributor)
25 Jun 2024Activity: Talk or presentation › Talk or presentation at a conference
Thesis
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Evaluatie van de efficiëntie van CRE mRNA-geïnduceerde recombinase in humane huidafgeleide mesenchymale stamcellen.
Rombaut, M. ((PhD) Student), Vanhaecke, T. (Co-promotor), De Kock, J. (Promotor) & Neuckermans, J. (Co-promotor), Vanhaecke, T. (Promotor), 2018Student thesis: Master's Thesis