Projects per year
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Dive into the research topics where Nico De Leu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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FWOTM1255: MACBETh: Uncovering the role of MACrophages in BETa cell (re)generation.
Willems, L., De Leu, N., Staels, W. & Van Ginderachter, J.
1/11/24 → 31/10/28
Project: Fundamental
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HERC66: 3D-CELLMAP: Unveiling complex cellular interactions in tissues through 3D super-resolution protein multiplex imaging
Movahedi, K., Rooman, I., Sermon, K., De Bundel, D., Fioravanti, A., Staels, W., Magez, S., Breckpot, K., De Kock, J., Laoui, D., Goyvaerts, C., Smolders, I., Van Ginderachter, J., Marcelino Rodrigues, R., De Leu, N., van Grunsven, L., Hernot, S., Peeters, E., Vanhaecke, T., De Veirman, K., Ruytinx, J., Van Schependom, J., Kortekaas, I. & Goossens, E.
1/05/24 → 31/05/28
Project: Fundamental
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FWOAL1090: Exploiting vascular signals to improve the functional maturation of iPSC-derived beta-like cells
1/01/23 → 31/12/26
Project: Fundamental
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FWOTM1142: Deciphering the involvement of iron metabolism in beta cell differentiation, maturation, and function.
Staels, W., De Leu, N., Heimberg, H. & Van Mulders, A.
1/11/22 → 31/10/26
Project: Fundamental
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A critical role for iron import through the transferrin receptor in developing ß-cells
Van Mulders, A., Staels, W., Willems, L., Coenen, S., Bourgeois, S., Ye, X., Tong, Y., Leuckx, G., Heremans, Y., De Koning, E., Carlotti, F., Scharfmann, R., Cnop, M. & De Leu, N., 16 Nov 2024, p. 486. 487 p.Research output: Unpublished contribution to conference › Unpublished abstract
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Comprehensive alpha, beta, and delta cell transcriptomics reveal an association of cellular aging with MHC class I upregulation
Staels, W., Berthault, C., Bourgeois, S., Laville, V., Lourenço, C., De Leu, N. & Scharfmann, R., Sept 2024, In: Molecular Metabolism. 87, 14 p., 101990.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Downloads (Pure) -
Dose-Dependent Effects of Murine Anti-Thymocyte Globulin (mATG) on Type 1 Diabetes (T1D) Development in Non-Obese Diabetic (NOD) Mice
Degroote, L., Wouters, A., Lemaitre, P., Mathieu, C., Gysemans, C., De Leu, N. & Staels, W., 7 Nov 2024.Research output: Unpublished contribution to conference › Poster
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ER stress relief drives ß-cell proliferation
Bourgeois, S., Van Mulders, A., Leuckx, G., Heremans, Y., Willems, L., Coenen, S., Degroote, L., Pierreux, J., Kancheva, D., Scheyltjens, I., Movahedi, K., Carlotti, F., de Koning, E., Yi, X., Vinci, C., Tong, Y., Cnop, M., Heimberg, H., De Leu, N. & Staels, W., Sept 2024, Biorxiv.Research output: Working paper › Preprint
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ER stress relief drives ß-cell proliferation
Bourgeois, S., Staels, W., Van Mulders, A., Willems, L., Coenen, S., Degroote, L., Pierreux, J., Leuckx, G., Heremans, Y., De Leu, N., Heimberg, H., Cnop, M., Ye, X., Movahedi, K., Kancheva, D., Scheyltjens, I., de, K. E. & Carlotti, F., 16 Nov 2024, p. 316. 317 p.Research output: Unpublished contribution to conference › Unpublished abstract
Prizes
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Belgian Endocrine Society, annual lecture
De Leu, Nico (Recipient), 2015
Prize: National/international honour
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Belgian Endocrine Society Annual Lecture Award
De Leu, Nico (Recipient), 2015
Prize: Prize (including medals and awards)
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McKinsey and Company Scientific Award
De Leu, Nico (Recipient), 2015
Prize: Prize (including medals and awards)
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Novo Nordisk prijs voor Diabetologie
De Leu, Nico (Recipient), 2018
Prize: National/international honour
Activities
- 10 Talk or presentation at a workshop/seminar
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Manipulating VEGF-A signaling for beta cell (re)generation and transplantation
Nico De Leu (Speaker)
2 Oct 2018Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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VEGF-A, islet endothelial cells and beta cell (re)generation
Nico De Leu (Speaker)
2 Jun 2017Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Beta cell regeneration and normoglycemia restoration in diabetic mice through myeloid-cell-driven angiogenesis
Nico De Leu (Speaker)
5 Apr 2011Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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VEGF-A, a key determinant for beta cell function and replication
Nico De Leu (Speaker)
21 Jan 2010 → 22 Jan 2010Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Beta cell regeneration and normoglycemia restoration in diabetic mice through VEGF-A-driven angiogenesis
Nico De Leu (Speaker)
16 Dec 2010 → 18 Dec 2010Activity: Talk or presentation › Talk or presentation at a workshop/seminar
Thesis
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Can beta cell injury induce homing of an intravenous injected stem cell line, seRM26, to pancreas?
Author: De Leu, N. & Heimberg, H., 2005Supervisor: Heimberg, H. (Promotor)
Student thesis: Master's Thesis