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Dive into the research topics where Paul Claes is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Studying the role of the cystine/glutamate antiporter System Xc- in hereditary tyrosinemia type 1: a pilot study
Del'Haye, G., Neuckermans, J., Stinckens, M., Liveyns, A. W., Claes, P., Mortier, A., Massie, A., Vanhaecke, T. & De Kock, J., 22 Oct 2025, (Unpublished).Research output: Unpublished contribution to conference › Poster
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An AAV-mediated liver-directed gene therapy metabolically corrects alkaptonuria in an Hgd deficient mouse model
Lequeue, S., Norman, B. P., Neuckermans, J., Colemonts-Vroninks, H., Hughes, J. H., Claes, P., Heymans, A., Ranganath, L., Gallagher, J., Vanhaecke, T., Bou-Gharios, G. & De Kock, J., 14 Aug 2023.Research output: Unpublished contribution to conference › Poster
Open Access -
Hereditary Tyrosinemia Type 1 Mice under Continuous Nitisinone Treatment Display Remnants of an Uncorrected Liver Disease Phenotype
Neuckermans, J., Lequeue, S., Claes, P., Heymans, A., Hughes, J. H., Colemonts-Vroninks, H., Marcélis, L., Casimir, G., Goyens, P., Martens, G. A., Gallagher, J. A., Vanhaecke, T., Bou-Gharios, G. & De Kock, J., 11 Mar 2023, In: Genes. 14, 3, 15 p., 693.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)113 Downloads (Pure) -
Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways
Colemonts-Vroninks, H., Norman, B., Van Laere, S., Davison, A., Marcélis, L., Casimir, G., Goyens, P., Claes, P., De Bundel, D., Martens, G. A., Ranganath, L. R., Vanhaecke, T., Gallagher, J. & De Kock, J., Sept 2023, In: Genes&Diseases. 10, 5, p. 1759-1762 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)60 Downloads (Pure) -
Oxidative Stress, Glutathione Metabolism, and Liver Regeneration Pathways Are Activated in Hereditary Tyrosinemia Type 1 Mice upon Short-Term Nitisinone Discontinuation
Colemonts-Vroninks, H., Neuckermans, J., Marcelis, L., Claes, P., Branson, S., Casimir, G., Goyens, P., Martens, G. A., Vanhaecke, T. & De Kock, J., Jan 2021, In: Genes. 12, 1, p. 1-16 16 p., 3.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)234 Downloads (Pure)
Datasets
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Gene expression profiling of Fah- and Hgd-deficient mouse livers upon short-term nitisinone discontinuation
Neuckermans, J. (Creator), Claes, P. (Researcher), Heymans, A. (Researcher), Colemonts-Vroninks, H. (Project Member), Martens, G. (Project Member), Vanhaecke, T. (Supervisor) & De Kock, J. (Supervisor), NCBI Gene Expression Omnibus, 4 Apr 2023
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE225001
Dataset