Research output per year
Research output per year
Personal profile
Expertise
I am interested in the function of system XC- on immune cells in the context of pancreatic cancer. To study this, I generate mice where system XC is exclusively absent on immune cells using bone marrow transplantation.
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Collaborations and top research areas from the last five years
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Research output
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Pancreatic acinar cell fate relies on system xC- to prevent ferroptosis during stress
Pan, Z., Van den Bossche, J-L., Rodriguez-Aznar, E., Janssen, P., Lara, O., Ates, G., Massie, A., De Paep, D. L., Houbracken, I., Mambretti, M. & Rooman, I., 21 Aug 2023, In: Cell & Death Disease. 14, 8, 10 p., 536.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Author Correction: Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes (Nature, (2022), 606, 7915, (776-784), 10.1038/s41586-022-04754-6)
Maschalidi, S., Mehrotra, P., Keçeli, B. N., De Cleene, H. K. L., Lecomte, K., Van der Cruyssen, R., Janssen, P., Pinney, J., van Loo, G., Elewaut, D., Massie, A., Hoste, E. & Ravichandran, K. S., 27 Jul 2022, In: Nature. 608, 7923, p. E29-E29 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Lifespan extension with preservation of hippocampal function in aged system xc--deficient male mice
Verbruggen, L., Ates, G., Lara, O., De Munck, J., Villers, A., De Pauw, L., Ottestad-Hansen, S., Kobayashi, S., Beckers, P., Janssen, P., Sato, H., Zhou, Y., Hermans, E., Njemini, R., Arckens, L., Danbolt, N. C., De Bundel, D., Aerts, J. L., Barbé, K., Guillaume, B. & 3 others, , Apr 2022, In: Molecular Psychiatry. 27, 4, p. 2355-2368 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)37 Downloads (Pure) -
Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes
Maschalidi, S., Mehrotra, P., Keçeli, B. N., De Cleene, H. K. L., Lecomte, K., Van der Cruyssen, R., Janssen, P., Pinney, J., van Loo, G., Elewaut, D., Massie, A., Hoste, E. & Ravichandran, K. S., 23 Jun 2022, In: Nature. 606, 7915, p. 776-784 9 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Citations (Scopus) -
Targeting system xc- in a mouse pancreatic cancer model reduces tumor growth, neuroinflammation and mood disturbances
Janssen, P., 22 May 2022.Research output: Unpublished contribution to conference › Poster
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Belgian Society for Neuroscience (BSN) Meeting 2022
Pauline Janssen (Participant)
22 May 2022Activity: Participating in or organising an event › Participation in conference
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Science Mix: from genotype to phenotype
Pauline Janssen (Chair)
2021Activity: Participating in or organising an event › Participating in or organizing a school event
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Science Mix - From genotype to phenotype
Pauline Janssen (Chair)
30 Oct 2019Activity: Participating in or organising an event › Participating in or organizing a school event