Projects per year
Personal profile
Education/Academic qualification
Pharmaceutical and Pharmacological Sciences, Researcher, PhD, Enhancing the immunogenicity and antitumor efficacy of virotherapy by supplementing an oncolytic virus with checkpoint inhibition and immunological cell death inducers, Research Foundation - Flanders
1 Jan 2019 → 31 Dec 2020
Award Date: 13 Dec 2018
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Projects
- 2 Finished
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ANI315: Understanding oncolytic herpes simplex virus type-1 induced cell death mechanisms and immunogenicity.
1/01/23 → 31/12/23
Project: Fundamental
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A combination of oncolytic HSV-1 and in vitro generated CD103+ dendritic cells induces anti-tumor immune responses in a mouse melanoma model
De Munck, J., Vanbellingen, S., Laeremans, T., D'haese, S., Kalus, P., Den Roover, S. & Aerts, J., 2023, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Fighting Fire with Fire: alleviating immune suppression in the tumor microenvironment by targeting complement inhibition
Vanbellingen, S., Nedyalkova, S., Kalus, P., De Munck, J., Van Mulders, A., Laeremans, T. & Aerts, J., 2023, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Oncolytic Herpes Simplex Virus Type 1 Induces Immunogenic Cell Death Resulting in Maturation of BDCA-1+ Myeloid Dendritic Cells
Kalus, P., De Munck, J., Vanbellingen, S., Carreer, L., Laeremans, T., Broos, K., Dufait, I., Schwarze, J. K., Van Riet, I., Neyns, B., Breckpot, K. & Aerts, J., May 2022, In: International Journal of Molecular Sciences. 23, 9, 17 p., 4865.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)65 Downloads (Pure) -
S1-28 The oncolytic HSV-1 virus T-VEC induces immunogenic cell death of melanoma cells and efficiently matures monocyte derived as well as BDCA-1+/BDCA-3+ myeloid dendritic cells
De Munck, J., Kalus, P., Smets, H., Broos, K., Tijtgat, J., Van Riet, I., Dufait, I., Schwarze, J. K., Goyvaerts, C., Neyns, B., Tuyaerts, S., Breckpot, K. & Aerts, J., 10 May 2021.Research output: Unpublished contribution to conference › Poster
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The development of methods to detect the different hallmarks of immunogenic cell death
De Munck, J., Kalus, P., Smets, H., Breckpot, K. & Aerts, J., 2020.Research output: Unpublished contribution to conference › Poster
Thesis
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Towards an integrated immunotherapy appoach for melanoma using Herpes Simplex Virus 1 derived oncolytic viruses
Author: Devoogdt, N., Aerts, J. & Kalus, P., 21 Jun 2018Student thesis: Master's Thesis