Projects per year
Personal profile
Expertise
Expertise: Tumor immunology.
We evaluate the use of single domain antibodies (sdAbs), also known as nanobodies, as targeting moieties for therapeutic and diagnostic applications.
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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FWOSB43: Nanobody-mediated imaging and blocking of the inhibitory receptor LAG-3
Lecocq, Q., Breckpot, K., Devoogdt, N. & Keyaerts, M.
1/01/18 → 31/12/21
Project: Fundamental
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ANI173: Nanobody-mediated imaging and blocking of the inhibitory receptor LAG3.
1/10/16 → 30/09/17
Project: Fundamental
Research output
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Accepted poster session at ImmunoRad 2023: Targeted alpha therapy using Actinium-225 radiolabeled single domain antibodies induces antigen-specific immune responses and instills immunomodulation both systemically and at the tumor microenvironment
Ertveldt, T., Krasniqi, A., Ceuppens, H., Puttemans, J., Dekempeneer, Y., De Jonghe, K., de Mey, W., Lecocq, Q., De Vlaeminck, Y., Awad, R. M., Goyvaerts, C., De Veirman, K., Morgenstern, A., Bruchertseifer, F., Keyaerts, M., Devoogdt, N., D'Huyvetter, M. & Breckpot, K., 27 Sep 2023.Research output: Unpublished contribution to conference › Poster
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Phase I Study of [68Ga]Ga-Anti-CD206-sdAb for PET/CT Assessment of Protumorigenic Macrophage Presence in Solid Tumors (MMR Phase I)
Gondry, O., Xavier, C., Raes, L., Heemskerk, J., Devoogdt, N., Everaert, H., Breckpot, K., Lecocq, Q., Decoster, L., Fontaine, C., Schallier, D., Aspeslagh, S., Vaneycken, I., Raes, G., Van Ginderachter, J. A., Lahoutte, T., Caveliers, V. & Keyaerts, M., Sep 2023, In: Journal of Nuclear Medicine. 64, 9, p. 1378-1384 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)1 Downloads (Pure) -
Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment
Ertveldt, T., Krasniqi, A., Ceuppens, H., Puttemans, J., Dekempeneer, Y., De Jonghe, K., de Mey, W., Lecocq, Q., De Vlaeminck, Y., Awad, R. M., Goyvaerts, C., De Veirman, K., Morgenstern, A., Bruchertseifer, F., Keyaerts, M., Devoogdt, N., D'Huyvetter, M. & Breckpot, K., 1 May 2023, In: Journal of Nuclear Medicine. 64, 5, p. 751-758 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
168P Characterization of the lung tumor microenvironment upon anti-PD-L1 therapy reveals an ambiguous role for TNF-α
De Ridder, K., Locy, H., Piccioni, E., Zuazo Ibarra, M., Awad, R. M., Verhulst, S., Van Bulck, M., De Vlaeminck, Y., Lecocq, Q., Reijmen, E., de Mey, W., De Beck, L., Ertveldt, T., Escors, D., Keyaerts, M., Breckpot, K. & Goyvaerts, C., 30 Mar 2022, In: Annals of Oncology. 33, S2, p. 109-109 1 p.Research output: Contribution to journal › Meeting abstract (Journal)
Open Access -
Characterization of the lung tumor microenvironment upon anti-PD-L1 therapy reveals an ambiguous role for TNF-α
De Ridder, K., Locy, H., Piccioni, E., Zuazo, M. I., Awad, R. M., Verhulst, S., Van Bulck, M., De Vlaeminck, Y., Lecocq, Q., Reijmen, E., de Mey, W., De Beck, L., Ertveldt, T., Escors, D., Keyaerts, M., Breckpot, K. & Goyvaerts, C., 6 Aug 2022.Research output: Unpublished contribution to conference › Poster
Prizes
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Best Presentation Award @ ORC day 18/11/2019
Lecocq, Quentin (Recipient), 18 Nov 2019
Prize: Prize (including medals and awards)
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Certificat of Young Speaker Award
Lecocq, Quentin (Recipient), Broos, K. (Recipient), Bridoux, Jessica (Recipient), Raes, Geert (Recipient), Xavier, Catarina (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient) & Breckpot, Karine (Recipient), 1 Feb 2019
Prize: Prize (including medals and awards)
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CIMT Travel Award 2019
Lecocq, Quentin (Recipient), 21 May 2019
Prize: Prize (including medals and awards)
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ESMI presentation award for best oral presentation
Bridoux, Jessica (Recipient), Broos, K. (Recipient), Lecocq, Quentin (Recipient), Crauwels, M. (Recipient), Martin, Charlotte (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, Steven (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, Geert (Recipient), Breckpot, Karine (Recipient), Muyldermans, Serge (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient), Caveliers, Vicky (Recipient) & Xavier, Catarina (Recipient), 17 Jan 2020
Prize: Prize (including medals and awards)
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Knowledge for Growth 2018 Ghent - poster award
Broos, K. (Recipient), Lecocq, Quentin (Recipient), Bridoux, Jessica (Recipient), Raes, Geert (Recipient), Xavier, Catarina (Recipient), Keyaerts, Marleen (Recipient), Devoogdt, Nick (Recipient) & Breckpot, Karine (Recipient), 18 May 2018
Prize: Prize (including medals and awards)
Activities
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Using the site-specific radiolabeling of a PD-L1 nanobody via maleimide–cysteine chemistry to develop a PET-tracer as screening tool for personalized oncology treatment
Dora Mugoli Chigoho (Speaker), Jessica Bridoux (Speaker), Catarina Xavier (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker), Nick Devoogdt (Speaker), Karine Breckpot (Speaker), Robin Maximilian Awad (Speaker) & Quentin Lecocq (Speaker)
7 May 2022Activity: Talk or presentation › Talk or presentation at a conference
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Nanobody-mediated imaging of the immune checkpoint LAG-3
Quentin Lecocq (Speaker)
4 Feb 2021Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Nanobody-mediated imaging of the immune checkpoint LAG-3
Quentin Lecocq (Speaker)
18 Jan 2021Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Noninvasive imaging and inhibition of human programmed death ligand 1 (PD-L1) using nanobody K2 to improve cancer immunotherapy
Robin Maximilian Awad (Contributor), Dora Mugoli Chigoho (Contributor), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Katty Zeven (Contributor), Thomas Ertveldt (Contributor), Lien De Beck (Contributor), Hannelore Ceuppens (Contributor), Yannick De Vlaeminck (Contributor), Cleo Goyvaerts (Contributor), Steve Schoonooghe (Contributor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Geert Raes (Contributor), Marleen Keyaerts (Contributor), Nick Devoogdt (Contributor) & Karine Breckpot (Speaker)
25 Oct 2021 → 26 Oct 2021Activity: Talk or presentation › Talk or presentation at a conference
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2020-73
Nick Devoogdt (Supervisor), Karine Breckpot (Contributor) & Quentin Lecocq (Contributor)
2020Activity: Other
Press/Media
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Interview by Immune Image consortium of Quentin Lecocq
25/02/21
1 Media contribution
Press/Media: Other
Thesis
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Nanobody-mediated imaging and blocking of the inhibitory receptor LAG-3
Author: Lecocq, Q., Breckpot, K., Devoogdt, N. & Keyaerts, M., 23 Nov 2021Supervisor: Breckpot, K. (Promotor), Devoogdt, N. (Promotor) & Keyaerts, M. (Co-promotor)
Student thesis: Doctoral Thesis
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Nanobody-mediated imaging and inhibition of the Immune checkpoint ligand PD-L1
Author: Breckpot, K. & Lecocq, Q., 16 Jun 2016Supervisor: Devoogdt, N. (Promotor), Keyaerts, M. (Promotor) & Broos, K. (Promotor)
Student thesis: Master's Thesis
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Nanobody-mediated imaging and inhibition of the immune checkpoint ligans PD-L1
Author: Lecocq, Q., Breckpot, K., Devoogdt, N. & Hernot, S., 16 Jun 2016Student thesis: Master's Thesis