Projects per year
Personal profile
Expertise
- Fundamental Research in Eukaryotic Gene Expression. Protein-DNA interaction. Protein Structure and Action. (X-ray crystallography) Antibody Engineering. Protein engineering. (Site directed mutagenesis/Enzym kinetics).
- Cloning and production of recombinant antibody fragments derived from camelidae
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Dive into the research topics where Serge Muyldermans is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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IOFPOC51: IOF POC Project SYNALI : Development and application of a Synthetic Nanobody Library
Devoogdt, N., Muyldermans, S., Sterckx, Y. & Caljon, G.
1/01/22 → 31/12/23
Project: Applied
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FWOAL879: Nanobody-based inhibitors of connexin hemichannels and pannexin channels as novel therapeutics for the treatment of inflammatory hepatic and cardiovascular diseases.
Vinken, M., Muyldermans, S. & Kwak, B. R.
1/01/18 → 31/12/21
Project: Fundamental
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ANI192: Evaluation of the theranostic potential of Nanobodies against Acute Myeloid Leukemia Stem Cell Markers
Muyldermans, S., Romao, E. & Devoogdt, N.
1/10/17 → 14/11/18
Project: Fundamental
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FWOAL856: ERA-NET NEURON cofund JTC 2016: 'Spinal cord repair by endogenous stem cells from the spinal niche'
1/07/17 → 30/06/19
Project: Fundamental
Research output
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AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model
Marino, M., Zhou, L., Rincon, M. Y., Callaerts-Vegh, Z., Verhaert, J., Wahis, J., Creemers, E., Yshii, L., Wierda, K., Saito, T., Marneffe, C., Voytyuk, I., Wouters, Y., Dewilde, M., Duqué, S. I., Vincke, C., Levites, Y., Golde, T. E., Saido, T. C., Muyldermans, S. & 3 others, , 7 Apr 2022, In: EMBO Molecular Medicine. 14, 4, p. e09824 e09824.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Nanobodies: From Serendipitous Discovery of Heavy Chain-Only Antibodies in Camelids to a Wide Range of Useful Applications
Ji, F., Ren, J., Vincke, C., Jia, L. & Muyldermans, S., 2022, In: Methods in Molecular Biology: Experimental Cholestasis Research . 2446, p. 3-17 15 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Nanobodies as binding-chaperones stabilize the recombinant Bombyx mori acetylcholinesterase and protect the enzyme activity in pesticide detection
Cai, J., Romao, E., Li, J., Li, L., Wang, Z., Li, Y., Yang, J., Shen, Y., Xu, Z., Muyldermans, S. & Wang, H., Apr 2022, In: Enzyme and Microbial Technology. 155, 109992.Research output: Contribution to journal › Article › peer-review
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Neutralizing Dromedary-Derived Nanobodies Against BotI-Like Toxin From the Most Hazardous Scorpion Venom in the Middle East and North Africa Region
Ben Abderrazek, R., Ksouri, A., Idoudi, F., Dhaouadi, S., Hamdi, E., Vincke, C., Farah, A., Benlasfar, Z., Majdoub, H., El Ayeb, M., Muyldermans, S. & Bouhaouala-Zahar, B., 19 Apr 2022, In: Frontiers in Immunology. 13, 13 p., 863012.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Sensitive Protein Detection Using Site-Specifically Oligonucleotide-Conjugated Nanobodies
Al-Amin, R. A., Muthelo, P. M., Abdurakhmanov, E., Vincke, C., Amin, S. P., Muyldermans, S., Danielson, U. H. & Landegren, U., 19 Jul 2022, In: Analytical Chemistry. 94, 28, p. 10054-10061 8 p.Research output: Contribution to journal › Article › peer-review
Prizes
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ESMI presentation award for best oral presentation
Bridoux, Jessica (Recipient), Broos, K. (Recipient), Lecocq, Quentin (Recipient), Crauwels, M. (Recipient), Martin, Charlotte (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, Steven (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, Geert (Recipient), Breckpot, Karine (Recipient), Muyldermans, Serge (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient), Caveliers, Vicky (Recipient) & Xavier, Catarina (Recipient), 17 Jan 2020
Prize: Prize (including medals and awards)
Activities
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Biomolecules (Journal)
Nick Devoogdt (Editor), Serge Muyldermans (Editor), Timo De Groof (Editor) & Sophie Hernot (Editor)
2021 → …Activity: Publication peer-review and editorial work › Editorial activity
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Immuno-PET imaging using the hPD-L1 Nanobody: Radiolabelling strategies
Jessica Bridoux (Speaker), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Maxine Crauwels (Contributor), Charlotte Martin (Contributor), Frederik Cleeren (Contributor), Mikhail Krivoshapov (Speaker), Steven Ballet (Speaker), G. Bormans (Speaker), Geert Raes (Speaker), Karine Breckpot (Speaker), Serge Muyldermans (Speaker), Magnus Schou (Speaker), Chad Elmore (Speaker), Nick Devoogdt (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker) & Catarina Xavier (Speaker)
14 Jan 2020Activity: Talk or presentation › Talk or presentation at a conference
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Human PD-L1 Nanobody for PET imaging: A site-specific radiolabeling strategy
Jessica Bridoux (Speaker), Katrijn Broos (Contributor), Maxine Crauwels (Contributor), Quentin Lecocq (Contributor), C Martin (Contributor), Frederik Cleeren (Contributor), Guy Bormans (Contributor), Steven Ballet (Contributor), Vicky Caveliers (Contributor), Geert Raes (Contributor), Karine Breckpot (Contributor), Serge Muyldermans (Contributor), Nick Devoogdt (Contributor), Marleen Keyaerts (Contributor) & Catarina Xavier (Contributor)
21 Mar 2018Activity: Talk or presentation › Talk or presentation at a conference
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Specificity evaluation and disease monitoring in arthritis imaging with complement receptor of the Ig superfamily targeting nanobodies
Fang Zheng (Speaker), Tony Lahoutte (Contributor), Serge Muyldermans (Contributor), Patrick De Baetselier (Contributor), Steve Schoonooghe (Contributor), Nick Devoogdt (Contributor) & Geert Raes (Contributor)
13 Sep 2017 → 16 Sep 2017Activity: Talk or presentation › Talk or presentation at a conference
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A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic islets
Alexander Balhuizen (Contributor), Iris Mathijs (Contributor), Sam Massa (Contributor), Jean-Valery Turatsinze (Contributor), Jens De Vos (Contributor), Stéphane Demine (Contributor), Catarina Xavier (Contributor), Olatz Villate (Contributor), Isabelle Millard (Contributor), Dominique Egrise (Contributor), Carmen Capito (Contributor), Raphael Scharfmann (Contributor), Peter In't Veld (Contributor), Piero Marchetti (Contributor), Serge Muyldermans (Contributor), Serge Goldman (Contributor), Tony Lahoutte (Contributor), Luc Bouwens (Contributor), Decio Eizirik (Contributor) & Nick Devoogdt (Speaker)
5 Apr 2017 → 7 Apr 2017Activity: Talk or presentation › Talk or presentation at a conference
Thesis
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Bead based immunoassay of HER2 ECD domain using nanobodies
Author: Adaga, E., Muyldermans, S., De Pauw, P. & Devoogdt, N., 1 Sep 2015Student thesis: Master's Thesis
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Conversion of Nanobodies to Fluorescent probes with conserved size and functionality
Author: Nguyen, T. N. H., Xavier, C., Muyldermans, S. & Pauw, De, P., 5 Sep 2014Student thesis: Master's Thesis
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Development of innovative nanobody-based strategies to improve the diagnosis of human toxocariasis
Author: Devoogdt, N., Morales Yanez, F., Muyldermans, S., Polman, K., Peeters, E., Versées, W., Claerebout, E. & De Wael, K., 5 Jul 2019Student thesis: Doctoral Thesis
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Development of novel fluorescent reporters for Sulfolobus acidocaldarius and their application to build a biosensor strain
Author: Linussio, J., Peeters, E., Willaert, R. & Muyldermans, S., 27 Jun 2016Supervisor: Sybers, D. (Advisor)
Student thesis: Master's Thesis
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Diagnostic potential of a Nanobody directed against Trypanosoma congolense fructose-1,6-bisphosphate aldolase
Author: Lee, F., Muyldermans, S., Van Ginderachter, J., Sterckx, Y. & Magez, S., Jun 2016Student thesis: Master's Thesis