Projects per year
Personal profile
Expertise
- Fundamental Research in Eukaryotic Gene Expression. Protein-DNA interaction. Protein Structure and Action. (X-ray crystallography) Antibody Engineering. Protein engineering. (Site directed mutagenesis/Enzym kinetics).
- Cloning and production of recombinant antibody fragments derived from camelidae
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Dive into the research topics where Serge Muyldermans is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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IOFPOC51: IOF POC Project SYNALI : Development and application of a Synthetic Nanobody Library
Devoogdt, N., Muyldermans, S., Sterckx, Y. & Caljon, G.
1/01/22 → 25/04/25
Project: Applied
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FWOAL879: Nanobody-based inhibitors of connexin hemichannels and pannexin channels as novel therapeutics for the treatment of inflammatory hepatic and cardiovascular diseases.
Vinken, M., Muyldermans, S. & Kwak, B. R.
1/01/18 → 31/12/21
Project: Fundamental
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ANI192: Evaluation of the theranostic potential of Nanobodies against Acute Myeloid Leukemia Stem Cell Markers
Muyldermans, S., Romao, E. & Devoogdt, N.
1/10/17 → 14/11/18
Project: Fundamental
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FWOAL856: ERA-NET NEURON cofund JTC 2016: 'Spinal cord repair by endogenous stem cells from the spinal niche'
1/07/17 → 30/06/19
Project: Fundamental
Research output
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Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal β-1,3-Glucanosyltransferases
Redrado-Hernández, S., Macías-León, J., Castro-López, J., Sanz, A. B., Dolader, E., Arias, M., González-Ramírez, A. M., Sánchez-Navarro, D., Petryk, Y., Farkaš, V., Vincke, C., Muyldermans, S., García-Barbazán, I., Del Agua, C., Zaragoza, O., Arroyo, J., Pardo, J., Gálvez, E. & Hurtado-Guerrero, R., 19 Aug 2024, In: Angewandte Chemie International Edition. 63, 34, e202405823.Research output: Contribution to journal › Article › peer-review
Open Access -
Epitope mapping of nanobodies binding the Alzheimer's disease receptor SORLA
Monti, G., Vincke, C., Lunding, M., Jensen, A. M. G., Madsen, P., Muyldermans, S., Kjolby, M. & Andersen, O. M., 20 Sep 2023, In: Journal of Biotechnology. 375, p. 17-27 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)19 Downloads (Pure) -
Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury
Van Campenhout, R., De Groof, T., Kadam, P., Kwak, B. R., Muyldermans, S., Devoogdt, N. & Vinken, M., 11 Oct 2023, In: Journal of Nanobiotechnology. 21, 1, p. 371 20 p., 371.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)29 Downloads (Pure) -
AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model
Marino, M., Zhou, L., Rincon, M. Y., Callaerts-Vegh, Z., Verhaert, J., Wahis, J., Creemers, E., Yshii, L., Wierda, K., Saito, T., Marneffe, C., Voytyuk, I., Wouters, Y., Dewilde, M., Duqué, S. I., Vincke, C., Levites, Y., Golde, T. E., Saido, T. C., Muyldermans, S. & 3 others, , 7 Apr 2022, In: EMBO Molecular Medicine. 14, 4, 21 p., e09824.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)261 Downloads (Pure) -
Nanobodies: From Serendipitous Discovery of Heavy Chain-Only Antibodies in Camelids to a Wide Range of Useful Applications
Ji, F., Ren, J., Vincke, C., Jia, L. & Muyldermans, S., 2022, In: Methods in Molecular Biology: Experimental Cholestasis Research . 2446, p. 3-17 15 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus)
Prizes
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ESMI presentation award for best oral presentation
Bridoux, Jessica (Recipient), Broos, K. (Recipient), Lecocq, Q. (Recipient), Crauwels, M. (Recipient), Martin, Charlotte (Recipient), Cleeren, F. (Recipient), Kondrashov, M. (Recipient), Ballet, Steven (Recipient), Bormans, G. (Recipient), Schou, M. (Recipient), Elmore, C. (Recipient), Raes, Geert (Recipient), Breckpot, Karine (Recipient), Muyldermans, Serge (Recipient), Devoogdt, Nick (Recipient), Keyaerts, Marleen (Recipient), Caveliers, Vicky (Recipient) & Xavier, C. (Recipient), 17 Jan 2020
Prize: Prize (including medals and awards)
Activities
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Nanobody-based pannexin1 channel inhibitors reduce inflammation in acute liver injury
Raf Van Campenhout (Speaker), Timo De Groof (Contributor), Prashant Kadam (Contributor), Brenda R. Kwak (Contributor), Serge Muyldermans (Contributor), Nick Devoogdt (Contributor) & Mathieu Vinken (Contributor)
24 Jul 2024 → 31 Jul 2024Activity: Talk or presentation › Talk or presentation at a conference
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Nanobody-based Panx1 channel inhibitors reduce inflammation in acute liver injury
Daan Peeters (Presenter), Timo De Groof (Contributor), Prashant Kadam (Contributor), Brenda R. Kwak (Contributor), Serge Muyldermans (Contributor), Nick Devoogdt (Contributor), Raf Van Campenhout (Contributor) & Mathieu Vinken (Contributor)
7 Oct 2024Activity: Talk or presentation › Talk or presentation at a conference
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Biomolecules (Journal)
Nick Devoogdt (Editor), Serge Muyldermans (Editor), Timo De Groof (Editor) & Sophie Hernot (Editor)
2021 → …Activity: Publication peer-review and editorial work › Editorial activity
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Immuno-PET imaging using the hPD-L1 Nanobody: Radiolabelling strategies
Jessica Bridoux (Speaker), Katrijn Broos (Contributor), Quentin Lecocq (Contributor), Maxine Crauwels (Contributor), Charlotte Martin (Contributor), Frederik Cleeren (Contributor), Mikhail Krivoshapov (Speaker), Steven Ballet (Speaker), G. Bormans (Speaker), Geert Raes (Speaker), Karine Breckpot (Speaker), Serge Muyldermans (Speaker), Magnus Schou (Speaker), Chad Elmore (Speaker), Nick Devoogdt (Speaker), Vicky Caveliers (Speaker), Marleen Keyaerts (Speaker) & Catarina Xavier (Speaker)
14 Jan 2020Activity: Talk or presentation › Talk or presentation at a conference
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Human PD-L1 Nanobody for PET imaging: A site-specific radiolabeling strategy
Jessica Bridoux (Speaker), Katrijn Broos (Contributor), Maxine Crauwels (Contributor), Quentin Lecocq (Contributor), C Martin (Contributor), Frederik Cleeren (Contributor), Guy Bormans (Contributor), Steven Ballet (Contributor), Vicky Caveliers (Contributor), Geert Raes (Contributor), Karine Breckpot (Contributor), Serge Muyldermans (Contributor), Nick Devoogdt (Contributor), Marleen Keyaerts (Contributor) & Catarina Xavier (Contributor)
21 Mar 2018Activity: Talk or presentation › Talk or presentation at a conference
Thesis
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Bead based immunoassay of HER2 ECD domain using nanobodies
Author: Adaga, E., Muyldermans, S., De Pauw, P. & Devoogdt, N., 1 Sep 2015Student thesis: Master's Thesis
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Conversion of Nanobodies to Fluorescent probes with conserved size and functionality
Author: Nguyen, T. N. H., Xavier, C., Muyldermans, S. & Pauw, De, P., 5 Sep 2014Student thesis: Master's Thesis
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Development of novel fluorescent reporters for Sulfolobus acidocaldarius and their application to build a biosensor strain
Author: Linussio, J., Peeters, E., Willaert, R. & Muyldermans, S., 27 Jun 2016Supervisor: Sybers, D. (Advisor)
Student thesis: Master's Thesis
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Diagnostic potential of a Nanobody directed against Trypanosoma congolense fructose-1,6-bisphosphate aldolase
Author: Lee, F., Muyldermans, S., Van Ginderachter, J., Sterckx, Y. & Magez, S., Jun 2016Student thesis: Master's Thesis
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Effect of different characteristics of radiometal labelled nanobodies on the kidney retention
Author: Crauwels, M., Xavier, C., Muyldermans, S. & Devoogdt, N., 26 Oct 2020Student thesis: Doctoral Thesis