Projects per year
Personal profile
Expertise
Basic research related to the development of in vitro alternative methods:
- Human liver-based in vitro models
- Adult human skin-derived progenitor cells and their hepatic derivatives
- DILI screening, including steatosis, phospholipidosis and acute liver failure
- Flow cytometry-based high throughput screening of various hepatic cell models, for live/dead cell analysis, lipid and phospholipid accumulation
- Microscopy-based high content analysis for lipid and mitochondrial deregulation analysis
- Genotoxicant-specific qPCR array
- Transcriptomics and metabolomics readouts and analysis
- Risk assessment of consumer products
Education/Academic qualification
European Registered Toxicologist, Belgian Society of Toxicology
Doctor in Pharmaceutical Sciences, Vrije Universiteit Brussel
1994 → 2000
Certificate of successful pass of the exam of the Safety Assessment of Cosmetics in the EU - Training Course, Vrije Universiteit Brussel
2004
External positions
Member, Scientific Committee on Consumer Safety (SCCS) - DG SANCO
Fingerprint
Dive into the research topics where Tamara Vanhaecke is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
OZR3913: Cofinancing OZR FWO Hercules MZW - High-parametric single-cell protein profiling in intact tissues
Movahedi, K., van Grunsven, L., Rooman, I., Van Ginderachter, J., Smolders, I., Neyns, B., Vanhaecke, T., Laoui, D., Breckpot, K., De Veirman, K., Stijlemans, B., Van Schependom, J., Magez, S., Goyvaerts, C., De Kock, J., De Leu, N., Massie, A., Hellemans, K., Spits, C., De Bundel, D., De Trez, C., Hernot, S., Van Dooren, S., Aerts, J., Staels, W. & Tuyaerts, S.
25/02/22 → 25/02/26
Project: Fundamental
-
FOD119: An Interdisciplinary strategy to identify medical devices as a source of allergic or pyrogenic reactions
17/01/22 → 16/01/24
Project: Fundamental
-
BRGEOZ412: In vitro model using human skin stem cells to test drugs for advanced fatty liver disease
1/12/21 → 30/11/22
Project: Fundamental
-
FOD114: Characterisation and (quantitative) assessment of genotoxicity of mixtures of mycotoxins in food
15/09/21 → 14/09/23
Project: Fundamental
-
BRGEOZ402: Creation of a Brussels platform for alternative 3R methods: Brussels IC-3Rs
1/06/21 → 30/06/23
Project: Fundamental
Research output
-
From NAFLD to MAFLD: Aligning translational in vitro research to clinical insights
Gatzios, A., Rombaut, M., Buyl, K., De Kock, J., Rodrigues, R., Rogiers, V., Vanhaecke, T. & Boeckmans, J., 13 Jan 2022, In : Biomedicines. 10, 1, 19 p., 161.Research output: Contribution to journal › Article
Open AccessFile28 Downloads (Pure) -
Light triggered nanoscale biolistics for efficient intracellular delivery of functional macromolecules in mammalian cells
Fraire, J. C., Shaabani, E., Sharifiaghdam, M., Rombaut, M., Hinnekens, C., Hua, D., Ramon, J., Raes, L., Bolea-Fernandez, E., Brans, T., Vanhaecke, F., Borghgraef, P., Huang, C., Sauvage, F., Vanhaecke, T., De Kock, J., Xiong, R., De Smedt, S. & Braeckmans, K., Dec 2022, In : Nature Communications. 13, 1, p. 1996 1996.Research output: Contribution to journal › Article
Open Access -
Metabolic Signature of Ethanol-Induced Hepatotoxicity in HepaRG Cells by Liquid Chromatography–Mass Spectrometry-Based Untargeted Metabolomics
Iturrospe, E., Silva, K. M. D., Robeyns, R., Lavoir, M. V. D., Boeckmans, J., Vanhaecke, T., Nuijs, A. L. N. V. & Covaci, A., 1 Apr 2022, In : Journal of Proteome Research. 21, 4, p. 1153-1166 14 p.Research output: Contribution to journal › Article
-
Publisher Correction: Light triggered nanoscale biolistics for efficient intracellular delivery of functional macromolecules in mammalian cells
Fraire, J. C., Shaabani, E., Sharifiaghdam, M., Rombaut, M., Hinnekens, C., Hua, D., Ramon, J., Raes, L., Bolea-Fernandez, E., Brans, T., Vanhaecke, F., Borghgraef, P., Huang, C., Sauvage, F., Vanhaecke, T., De Kock, J., Xiong, R., De Smedt, S. & Braeckmans, K., 26 Apr 2022, In : Nature Communications. 13, 1, p. 2385Research output: Contribution to journal › Article
Open Access -
The Rise of Three Rs Centres and Platforms in Europe
Neuhaus, W., Reininger-Gutmann, B., Rinner, B., Plasenzotti, R., Wilflingseder, D., De Kock, J., Vanhaecke, T., Rogiers, V., Jírová, D., Kejlová, K., Knudsen, L. E., Nielsen, R. N., Kleuser, B., Kral, V., Thöne-Reineke, C., Hartung, T., Pallocca, G., Leist, M., Hippenstiel, S., Lang, A. & 45 others, , 2022, In : ATLA. Alternatives to Laboratory Animals. p. 2611929221099165Research output: Contribution to journal › Article
Open Access
Prizes
-
33. Forschungspreises zur Förderung methodischer Arbeiten mit dem Ziel der Einschränkung und des Ersatzes von Tierversuchen
Joery De Kock (Recipient), Robim Marcelino Rodrigues (Recipient), Tamara Vanhaecke (Recipient) & Vera Rogiers (Recipient), 2014
Prize: Prize (including medals and awards)
-
33. Forschungspreise zur Förderung methodischer Arbeiten mit dem Ziel der Einschränkung und des Ersatzes von Tierversuchen
Tamara Vanhaecke (Recipient), 4 Dec 2014
Prize: Prize (including medals and awards)
-
33. Forschungspreise zur Förderung methodischer Arbeiten mit dem Ziel der Einschränkung und des Ersatzes von Tierversuchen
Tamara Vanhaecke (Recipient), 2014
Prize: National/international honour
-
Best Paper Award 2007 from the Toxicological Society
Tamara Vanhaecke (Recipient), 2007
Prize: Prize (including medals and awards)
-
Establishment of an in vitro model of liver cell death
Tamara Vanhaecke (Recipient), 2008
Prize: Prize (including medals and awards)
Activities
-
A human hepatocyte-like cell based In Vitro model for hepatic insulin-driven De Novo Lipogenesis
Karolien Buyl (Speaker), Martine Vrints (Speaker), Ruani Fernando (Speaker), Thomas Van Eeckhoute (Speaker), Mia Jans (Speaker), Joost Boeckmans (Speaker), Robim Marcelino Rodrigues (Speaker), Vera Rogiers (Speaker), Jan Van Der Schueren (Speaker), Joery De Kock (Speaker), Tamara Vanhaecke (Speaker), Filip Beirinckx (Speaker)2020 → …Activity: Talk or presentation › Talk or presentation at a workshop/seminar
-
In vitro investigation of the anti-NASH properties of elafibranor and lanifibranor using a human stem cell-derived disease model
Joost Boeckmans (Speaker), Vera Rogiers (Contributor), Tamara Vanhaecke (Contributor), Robim Marcelino Rodrigues (Contributor)25 Feb 2019 → 26 Feb 2019Activity: Talk or presentation › Talk or presentation at a conference
-
Francqui lecture
Tamara Vanhaecke (Chair)27 Feb 2018Activity: Participating in or organising an event › Participation in conference
-
Francqui chair 2017-2018 awarded to prof. Maurice Whelan
Tamara Vanhaecke (Chair), Vera Rogiers (Chair)27 Feb 2018Activity: Participating in or organising an event › Participating in or organizing a public lecture/debate
-
Elafibranor reduces the expression of pannexin1 and CCL5 in a human-relevant skin stem cell-based model of non-alcoholic steatohepatitis (NASH)
Joost Boeckmans (Speaker), Alessandra Natale (Contributor), Karolien Buyl (Contributor), Joery De Kock (Contributor), Vera Rogiers (Contributor), Tamara Vanhaecke (Contributor), Robim Marcelino Rodrigues (Contributor)20 Mar 2018Activity: Talk or presentation › Talk or presentation at a workshop/seminar
Press / Media
-
Allergenen in geparfumeerde menstruatieproducten
Quinten Marcelis, Tamara Vanhaecke, Bart Desmedt, Eric Deconinck & Vera Rogiers
1/05/21
1 Media contribution
Press/Media: Research
-
-
Antitumorale farmaca dragen bij tot minder proefdiergebruik.
20/01/05
1 Media contribution
Press/Media: Other
-
Thesis
-
Alternative approaches to build quantitative structure-retention relationships
Author: Put, R., Vander Heyden, Y., Vanhaecke, T., Foriers, A., Smolders, I. J., Adams, E. & Kaliszan, R., 17 Sep 2008Supervisor: Vander Heyden, Y. (Promotor), Vanhaecke, T. (Jury), Foriers, A. (Jury), Smolders, I. (Jury), Adams, E. (External person) (Jury) & Kaliszan, R. (External person) (Jury)
Student thesis: Doctoral Thesis
-
Bepaling van de blootstelling aan een actief farmacon tijdens de productie ervan
Author: De Grande, F. & Vanhaecke, T., 2007Supervisor: Vanhaecke, T. (Promotor)
Student thesis: Master-after-master
-
Bepaling van het optimale mRNA elektroporatieprotocol voor humane huidafgeleide stamcellen.
Author: Neuckermans, J. & Vanhaecke, T., 2016Student thesis: Master's Thesis
-
Bepaling van nicotine en alkaloïden onzuiverheden in e-liquids beschikbaar op de Belgische markt.
Author: Sintobin, M. & Vanhaecke, T., 2017Student thesis: Master's Thesis
-
Beroepsmatige blootstelling aan mangaa bij lassers. Persoonlijke luchtbemonstering en biologische monitoring van mangaan in plasma, rode bloedcellen en urine
Author: Vanmarcke, E., Vanhaecke, T. & Hoet, P., 2009Supervisor: Vanhaecke, T. (Promotor) & Hoet, P. (External person) (Promotor)
Student thesis: Master-after-master