Projects per year
Personal profile
Expertise
Currently, i'm employed as a PhD-Candidate at the "Laboratory for Molecular and Cellular Therapy" (LMCT) researchgroup at the Vrije Universiteit Brussel. My work entails a jointproject between the LMCT and the "in Vivo Cellular and Molecular Imaging" (ICMI) researchgroups in which I’m investigating the immunogenic properties of targeted radionuclide therapy (TRT) mediated by single domain antibodies (sdAb’s).
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Projects
- 1 Finished
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FWOSB80: Combining targeted radionuclide therapy and cancer immunotherapy to advance precision medicine through innovation.
Breckpot, K., Devoogdt, N., D'Huyvetter, M., Keyaerts, M. & Ertveldt, T.
1/11/19 → 31/10/23
Project: Fundamental
Research output
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Accepted poster session at ImmunoRad 2023: Targeted alpha therapy using Actinium-225 radiolabeled single domain antibodies induces antigen-specific immune responses and instills immunomodulation both systemically and at the tumor microenvironment
Ertveldt, T., Krasniqi, A., Ceuppens, H., Puttemans, J., Dekempeneer, Y., De Jonghe, K., de Mey, W., Lecocq, Q., De Vlaeminck, Y., Awad, R. M., Goyvaerts, C., De Veirman, K., Morgenstern, A., Bruchertseifer, F., Keyaerts, M., Devoogdt, N., D'Huyvetter, M. & Breckpot, K., 27 Sep 2023.Research output: Unpublished contribution to conference › Poster
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Development and evaluation of nanobody tracers for noninvasive nuclear imaging of the immune-checkpoint TIGIT
Zeven, K., De Groof, T. W. M., Ceuppens, H., Awad, R. M., Ertveldt, T., de Mey, W., Meeus, F., Raes, G., Breckpot, K. & Devoogdt, N., 20 Sep 2023, In: Frontiers in Immunology. 14, 1, 16 p., 1268900.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
In vitro modelling of local gene therapy with IL-15/IL-15Rα and a PD-L1 antagonist in melanoma reveals an interplay between NK cells and CD4+ T cells
Awad, R. M., De Vlaeminck, Y., Meeus, F., Ertveldt, T., Zeven, K., Ceuppens, H., Goyvaerts, C., Verdonck, M., Salguero, G., Raes, G., Devoogdt, N. & Breckpot, K., Dec 2023, In: Scientific reports. 13, 1, p. 1-13 13 p., 18995.Research output: Contribution to journal › Article › peer-review
Open Access -
Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine
Ertveldt, T., Meulewaeter, S., De Vlaeminck, Y., Olarte, O., Broos, K., Van Calenbergh, S., Bourgeois, S., Deprez, J., Heremans, Y., Goyvaerts, C., Staels, W., De Smedt, S., Dewitte, H., Devoogdt, N., Keyaerts, M., Verbeke, R., Barbé, K., Lentacker, I. & Breckpot, K., 9 Oct 2023, In: Theranostics. 13, 15, p. 5483-5500 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Downloads (Pure) -
Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy
Funeh, C. N., Devoogdt, N., Chigoho, D. M., De Groof, T., Bridoux, J., Ertveldt, T., Covens, P. & D'Huyvetter, M., May 2023, In: Pharmaceutics. 15, 5, 31 p., 1378.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure)
Activities
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Cancer Biotherapy and Radiopharmaceuticals (Journal)
Thomas Ertveldt (Peer reviewer)
1 Oct 2023 → 31 Oct 2023Activity: Publication peer-review and editorial work › Publication peer-review
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SCK NMA-talk
Thomas Ertveldt (Presenter), Nick Devoogdt (Invited speaker) & Matthias D'Huyvetter (Contributor)
14 Nov 2023Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Development and evaluation of Nanobody tracers for non-invasive nuclear imaging of the next generation immune checkpoint TIGIT
Katty Zeven (Speaker), Timo De Groof (Contributor), Hannelore Ceuppens (Contributor), Robin Maximilian Awad (Contributor), Thomas Ertveldt (Contributor), Geert Raes (Contributor), Karine Breckpot (Contributor) & Nick Devoogdt (Contributor)
18 Sep 2023 → 20 Sep 2023Activity: Talk or presentation › Talk or presentation at a conference
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The development of radiolabeled nanobodies against the next-generation immune checkpoint TIGIT for non-invasive immune phenotyping of tumors
Katty Zeven (Speaker), Timo De Groof (Contributor), Robin Maximilian Awad (Contributor), Wout De Mey (Contributor), Thomas Ertveldt (Contributor), Hannelore Ceuppens (Contributor), Kevin De Jonghe (Contributor), Geert Raes (Contributor), Marleen Keyaerts (Contributor), Karine Breckpot (Contributor) & Nick Devoogdt (Contributor)
16 Mar 2023Activity: Talk or presentation › Talk or presentation at a conference
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Nanobody-mediated molecular imaging provides spatiotemporal insight in mRNA-vaccine-induced PD-L1 upregulation
Thomas Ertveldt (Speaker), Sofie Meulewaeter (Speaker), Ine Lentacker (Contributor), Rein Verbeke (Contributor), Stefaan De Smedt (Contributor), Oscar Javier Olarte Rodriguez (Contributor), Kurt Barbé (Contributor), Nick Devoogdt (Contributor), Marleen Keyaerts (Contributor), Heleen Dewitte (Contributor) & Karine Breckpot (Contributor)
19 Apr 2021Activity: Talk or presentation › Talk or presentation at a workshop/seminar
Thesis
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Immunogenic effect of targeted radionuclide therapy-induced tumor cell death
Author: Ertveldt, T., Breckpot, K., Keyaerts, M., D'Huyvetter, M. & Krasniqi, A., 15 Jun 2019Supervisor: Krasniqi, A. (Promotor)
Student thesis: Master's Thesis