Projects per year
Personal profile
Expertise
Prof Dr Tony Lahoutte is head of the department of nuclear medicine at UZ Brussel and head of the molecular imaging research unit at the Vrije Universiteit Brussel (VUB) in Belgium. In 2014 he co-founded the company Camel-IDS NV that is developing a pipeline of radio-immuno therapeutics where he is CSO. He obtained his medical degree in 1998 and started his research activities in combination with a residency program in nuclear medicine. His current research is focused on the development and clinical translation of molecular imaging probes and targeted radionuclide therapies for the detection and treatment of cancer.
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Projects
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FWOIRI7: FB-III (“FB triple-I”) : Flanders BioImaging: Integrating Imaging Infrastructure from cell to man.
1/02/21 → 31/01/23
Project: Fundamental
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EUAR14: H2020: Immune-Image: Specific Imaging of Immune Cell Dynamics Using Novel Tracer Strategies
Lahoutte, T., Devoogdt, N. & Keyaerts, M.
1/10/19 → 30/09/24
Project: Applied
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OZR3549: H2020: Immune-Image: Specific Imaging of Immune Cell Dynamics Using Novel Tracer Strategies (OZR Bonus EU)
1/10/19 → 30/09/24
Project: Fundamental
Research output
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Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality
Baudhuin, H., Puttemans, J., Hanssens, H., Vanwolleghem, P., Hernot, S., Raes, G., Xavier, C., Lahoutte, T. & Debie, P., 25 Apr 2021, In : Pharmaceuticals. 14, 5, 19 p., 407.Research output: Contribution to journal › Article
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Immunogenicity Risk Profile of Nanobodies
Ackaert, C., Smiejkowska, N., Xavier, C., Sterckx, Y. G. J., Denies, S., Stijlemans, B., Elkrim, Y., Devoogdt, N., Caveliers, V., Lahoutte, T., Muyldermans, S., Breckpot, K. & Keyaerts, M., 9 Mar 2021, In : Frontiers in Immunology. 12, 15 p., 632687.Research output: Contribution to journal › Article
2 Citations (Scopus) -
Phase I trial of 131I-GMIB-Anti-HER2-VHH1, a new promising candidate for HER2-targeted radionuclide therapy in breast cancer patients
D'Huyvetter, M., De Vos, J., Caveliers, V., Vaneycken, I., Heemskerk, J., Duhoux, F. P., Fontaine, C., Vanhoeij, M., Windhorst, A. D., van der Aa, F., Hendrikse, N. H., Eersels, J. L. E., Everaert, H., Gykiere, P., Devoogdt, N., Raes, G., Lahoutte, T. & Keyaerts, M., 4 Dec 2020, In : Journal of Nuclear Medicine.Research output: Contribution to journal › Article
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Preclinical Targeted α- and β−-Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies
Puttemans, J., Dekempeneer, Y., Eersels, J. L., Hanssens, H., Debie, P., Keyaerts, M., Breckpot, K., Lecocq, Q., Lahoutte, T., Windhorst, A. D., Van Der Aa, F., Morgenstern, A., Bruchertseifer, F., Devoogdt, N. & D'Huyvetter, M., 21 Apr 2020, In : Cancers. 12, 4, 1017.Research output: Contribution to journal › Article
Open AccessFile21 Downloads (Pure) -
Size and affinity kinetics of nanobodies influence targeting and penetration of solid tumours
Debie, P., Lafont, C., Defrise, M., Hansen, I., van Willigen, D. M., van Leeuwen, F. WB., Gijsbers, R., D'Huyvetter, M., Devoogdt, N., Lahoutte, T., Mollard, P. & Hernot, S., 10 Jan 2020, In : Journal of Controlled Release. 317, p. 34-42 9 p.Research output: Contribution to journal › Article
Open AccessFile31 Citations (Scopus)64 Downloads (Pure)
Prizes
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Professor Roger Van Geen Award
Tony Lahoutte (Recipient), Nov 2014
Prize: Prize (including medals and awards)
Activities
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2020-74
Tony Lahoutte (Supervisor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Herlinde Dierick (Contributor)2020Activity: Other
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2020-20
Tony Lahoutte (Supervisor), Isabel Remory (Contributor), Henri Vincent Baudhuin (Contributor), Marleen Keyaerts (Contributor), Odrade Gondry (Contributor)2020Activity: Other
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Design And Preclinical Evaluation Of A Single-label Bimodal Nanobody Tracer For Image-guided Surgery
Pieterjan Debie (Speaker), Bieke De Sloovere (Contributor), Danny M van Willigen (Contributor), Fijs WB van Leeuwen (Contributor), Catarina Xavier (Contributor), Nick Devoogdt (Contributor), Tony Lahoutte (Contributor), Sophie Hernot (Contributor)18 Oct 2019Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Nanobodies as pre-clinical imaging tools of new beta-cell biomarkers in Type 1 diabetes animal models
Rita Sofia Garcia Ribeiro (Speaker), Jessica Bridoux (Contributor), Stephane Demine (Contributor), Julie Kerr-Conte (Contributor), Julien Thevenet (Contributor), Raphael Scharfmann (Contributor), Decio Eizirik (Contributor), Tony Lahoutte (Contributor), Nick Devoogdt (Speaker)20 Mar 2019Activity: Talk or presentation › Talk or presentation at a conference
Press / Media
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Camel blood to fight cancer? This VUB spin-off is getting amazing results
Tony Lahoutte, Nick Devoogdt, Matthias D'Huyvetter, Jens De Vos & Claudia Mebis
17/11/17
1 Media contribution
Press/Media: Research
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Kanker bestrijden met elektrische fietsjes in het bloed
Tony Lahoutte, Ruth Devenyns, Nick Devoogdt, Matthias D'Huyvetter, Jens De Vos & Claudia Mebis
17/10/17
1 Media contribution
Press/Media: Research
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Nanobodies in de strijd tegen kanker
Tony Lahoutte & Marleen Keyaerts
1/09/17
1 Media contribution
Press/Media: Research
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Lama-antistoffen in strijd tegen kanker
Tony Lahoutte, Nick Devoogdt, Matthias D'Huyvetter, Jens De Vos & Claudia Mebis
30/03/17
1 Media contribution
Press/Media: Research
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Toelichting in het kader van Google X: Ontwikkeling van nanopartikels als diagnostische tool bij kankerbestrijding
29/10/14
1 Media contribution
Press/Media: Other
Thesis
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123I-2-Iodo-Tyrosine, a new tumour imaging agent: biodistribution, dosimetry and initial clinical evaluation in brain tumours
Author: Keyaerts, M., Bossuyt, A. & Lahoutte, T., 7 Jul 2005Supervisor: Bossuyt, A. (Promotor) & Lahoutte, T. (Advisor)
Student thesis: Master's Thesis
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123I-MIBG imaging: influence of specific activity on imaging parameters and application in a rat model of diabetes
Author: Goethals, L. & Lahoutte, T., 15 Jun 2008Supervisor: Lahoutte, T. (Promotor)
Student thesis: Master's Thesis
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A comparative study between pinhole gated myocardial perfusion SPECT and pinhole gated blood pool SPECT in rats with ligature of left descending coronary artery
Author: MALAKZADEH, M. & Lahoutte, T., 16 Dec 2005Supervisor: Lahoutte, T. (Promotor)
Student thesis: Master's Thesis
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Assessing dextran nanogels for intravenous small interfering RNA delivery
Author: Naeye, B., De Smedt, S., Demeester, J., Van Raemdonck, K. & Lahoutte, T., 12 Sep 2011Supervisor: Lahoutte, T. (Jury), De Smedt, S. (External person) (Promotor), Demeester, J. (External person) (Promotor) & Van Raemdonck, K. (External person) (Co-promotor)
Student thesis: Doctoral Thesis
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Assessment of Functional Beta Cell Mass in the Rodent Pancreas
Author: Chintinne, M., Pipeleers, D., Marichal, M., Ling, Z., Van Schravendijk, C., Lahoutte, T., Bouwens, L., Lenmark, A. & Roels, F., 7 Sep 2012Supervisor: Pipeleers, D. (Promotor), Marichal, M. (Co-promotor), Ling, Z. (Co-promotor), Van Schravendijk, C. (Jury), Lahoutte, T. (Jury), Bouwens, L. (Jury), Lernmark, A. (External person) (Jury) & Roels, F. (External person) (Jury)
Student thesis: Doctoral Thesis