Tony Lahoutte

Laarbeeklaan 101
1090 Jette
Belgium
Laarbeeklaan 101
1090 Brussels
Belgium

Source: Scopus
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Personal profile

Expertise

Prof Dr Tony Lahoutte is head of the department of nuclear medicine at UZ Brussel and head of the molecular imaging research unit at the Vrije Universiteit Brussel (VUB) in Belgium. In 2014 he co-founded the company Camel-IDS NV that is developing a pipeline of radio-immuno therapeutics where he is CSO. He obtained his medical degree in 1998 and started his research activities in combination with a residency program in nuclear medicine. His current research is focused on the development and clinical translation of molecular imaging probes and targeted radionuclide therapies for the detection and treatment of cancer.

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14 Active
33 Finished

EUAR33: H2020: CSA: EURAMED rocc-n-roll: title EURopeAn MEDical application and Radiation prOteCtion Concept: strategic research agenda aNd ROadmap interLinking to heaLth and digitisation aspects
Muylle, K. & Lahoutte, T.
1/09/20 → 31/08/23
Project: Fundamental
IOF3009: GEAR: Integrating a multimodal approach to address current challenges in immunotherapy (INTEGRAL)
Lahoutte, T., Devoogdt, N., Keyaerts, M., Van Ginderachter, J., Laoui, D., Raes, G., Breckpot, K. & Goyvaerts, C.
1/01/20 → 31/12/24
Project: Applied
OZR3549: H2020: Immune-Image: Specific Imaging of Immune Cell Dynamics Using Novel Tracer Strategies (OZR Bonus EU)
Lahoutte, T.
1/10/19 → 30/09/24
Project: Fundamental
EUAR14: H2020: Immune-Image: Specific Imaging of Immune Cell Dynamics Using Novel Tracer Strategies
Lahoutte, T., Devoogdt, N. & Keyaerts, M.
1/10/19 → 30/09/24
Project: Applied
IOF3005: IOF GEAR: NLITE
Lahoutte, T., Kuijk, M., Hernot, S. & Ingelberts, H.
21/12/18 → 20/12/23
Project: Applied

4720 Citations
41 h-Index
150 Article
66 Meeting abstract (Book)
37 Poster
30 Meeting abstract (Journal)
More

Immunogenicity Risk Profile of Nanobodies
Ackaert, C., Smiejkowska, N., Xavier, C., Sterckx, Y. G. J., Denies, S., Stijlemans, B., Elkrim, Y., Devoogdt, N., Caveliers, V., Lahoutte, T., Muyldermans, S., Breckpot, K. & Keyaerts, M., 2021, In : Frontiers in Immunology. 12, 15 p., 632687.
Research output: Contribution to journal › Article
1 Citation (Scopus)
Phase I trial of 131I-GMIB-Anti-HER2-VHH1, a new promising candidate for HER2-targeted radionuclide therapy in breast cancer patients
D'Huyvetter, M., De Vos, J., Caveliers, V., Vaneycken, I., Heemskerk, J., Duhoux, F. P., Fontaine, C., Vanhoeij, M., Windhorst, A. D., van der Aa, F., Hendrikse, N. H., Eersels, J. L. E., Everaert, H., Gykiere, P., Devoogdt, N., Raes, G., Lahoutte, T. & Keyaerts, M., 4 Dec 2020, In : Journal of Nuclear Medicine.
Research output: Contribution to journal › Article
Preclinical Targeted α- and β−-Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies
Puttemans, J., Dekempeneer, Y., Eersels, J. L., Hanssens, H., Debie, P., Keyaerts, M., Breckpot, K., Lecocq, Q., Lahoutte, T., Windhorst, A. D., Van Der Aa, F., Morgenstern, A., Bruchertseifer, F., Devoogdt, N. & D'Huyvetter, M., 21 Apr 2020, In : Cancers. 12, 4, 1017.
Research output: Contribution to journal › Article

Open Access
File
17 Downloads (Pure)
Size and affinity kinetics of nanobodies influence targeting and penetration of solid tumours
Debie, P., Lafont, C., Defrise, M., Hansen, I., van Willigen, D. M., van Leeuwen, F. WB., Gijsbers, R., D'Huyvetter, M., Devoogdt, N., Lahoutte, T., Mollard, P. & Hernot, S., 10 Jan 2020, In : Journal of Controlled Release. 317, p. 34-42 9 p.
Research output: Contribution to journal › Article

Open Access
File
30 Citations (Scopus)

63 Downloads (Pure)
Therapeutic Efficacy of 213Bi-labeled sdAbs in a Preclinical Model of Ovarian Cancer.
Dekempeneer, Y., Caveliers, V., Ooms, M., Maertens, D., Gysemans, M., Lahoutte, T., Xavier, C., Lecocq, Q., Maes, K., Covens, P., Miller, B. W., Bruchertseifer, F., Morgenstern, A., Cardinaels, T. & D'Huyvetter, M., 8 Sep 2020, In : Molecular Pharmaceutics. 17, 9, p. 3553-3566 14 p.
Research output: Contribution to journal › Article
1 Citation (Scopus)

Professor Roger Van Geen Award
Tony Lahoutte (Recipient), Nov 2014
Prize: Prize (including medals and awards)

26 Talk or presentation at a conference
5 Participation in conference
5 Membership of external research organisation
5 Other
More

2020-20
Tony Lahoutte (Supervisor), Isabel Remory (Contributor), Henri Vincent Baudhuin (Contributor), Marleen Keyaerts (Contributor), Odrade Gondry (Contributor)
2020
Activity: Other
2020-74
Tony Lahoutte (Supervisor), Vicky Caveliers (Contributor), Catarina Xavier (Contributor), Jessica Bridoux (Contributor), Herlinde Dierick (Contributor)
2020
Activity: Other
2020-75
Tony Lahoutte (Supervisor), Kristoff Muylle (Contributor)
2020
Activity: Other
Design And Preclinical Evaluation Of A Single-label Bimodal Nanobody Tracer For Image-guided Surgery
Pieterjan Debie (Speaker), Bieke De Sloovere (Contributor), Danny M van Willigen (Contributor), Fijs WB van Leeuwen (Contributor), Catarina Xavier (Contributor), Nick Devoogdt (Contributor), Tony Lahoutte (Contributor), Sophie Hernot (Contributor)
5 Sep 2019
Activity: Talk or presentation › Talk or presentation at a conference
2019-62
Tony Lahoutte (Supervisor), Marleen Keyaerts (Contributor)
2019
Activity: Other

Camel blood to fight cancer? This VUB spin-off is getting amazing results
Tony Lahoutte, Nick Devoogdt, Matthias D'Huyvetter, Jens De Vos & Claudia Mebis
17/11/17
1 Media contribution
Press/Media: Research
Kanker bestrijden met elektrische fietsjes in het bloed
Tony Lahoutte, Ruth Devenyns, Nick Devoogdt, Matthias D'Huyvetter, Jens De Vos & Claudia Mebis
17/10/17
1 Media contribution
Press/Media: Research
Nanobodies in de strijd tegen kanker
Tony Lahoutte & Marleen Keyaerts
1/09/17
1 Media contribution
Press/Media: Research
Lama-antistoffen in strijd tegen kanker
Tony Lahoutte, Nick Devoogdt, Matthias D'Huyvetter, Jens De Vos & Claudia Mebis
30/03/17
1 Media contribution
Press/Media: Research
Toelichting in het kader van Google X: Ontwikkeling van nanopartikels als diagnostische tool bij kankerbestrijding
Tony Lahoutte
29/10/14
1 Media contribution
Press/Media: Other

123I-2-Iodo-Tyrosine, a new tumour imaging agent: biodistribution, dosimetry and initial clinical evaluation in brain tumours
Author: Keyaerts, M., Bossuyt, A. & Lahoutte, T., 7 Jul 2005
Supervisor: Bossuyt, A. (Promotor) & Lahoutte, T. (Advisor)
Student thesis: Master's Thesis
123I-MIBG imaging: influence of specific activity on imaging parameters and application in a rat model of diabetes
Author: Goethals, L. & Lahoutte, T., 15 Jun 2008
Supervisor: Lahoutte, T. (Promotor)
Student thesis: Master's Thesis
A comparative study between pinhole gated myocardial perfusion SPECT and pinhole gated blood pool SPECT in rats with ligature of left descending coronary artery
Author: MALAKZADEH, M. & Lahoutte, T., 16 Dec 2005
Supervisor: Lahoutte, T. (Promotor)
Student thesis: Master's Thesis
Assessing dextran nanogels for intravenous small interfering RNA delivery
Author: Naeye, B., De Smedt, S., Demeester, J., Van Raemdonck, K. & Lahoutte, T., 12 Sep 2011
Supervisor: Lahoutte, T. (Jury), De Smedt, S. (External person) (Promotor), Demeester, J. (External person) (Promotor) & Van Raemdonck, K. (External person) (Co-promotor)
Student thesis: Doctoral Thesis
Assessment of Functional Beta Cell Mass in the Rodent Pancreas
Author: Chintinne, M., Pipeleers, D., Marichal, M., Ling, Z., Van Schravendijk, C., Lahoutte, T., Bouwens, L., Lenmark, A. & Roels, F., 7 Sep 2012
Supervisor: Pipeleers, D. (Promotor), Marichal, M. (Co-promotor), Ling, Z. (Co-promotor), Van Schravendijk, C. (Jury), Lahoutte, T. (Jury), Bouwens, L. (Jury), Lernmark, A. (External person) (Jury) & Roels, F. (External person) (Jury)
Student thesis: Doctoral Thesis