Personal profile
Expertise
Prof Dr Tony Lahoutte is head of the department of nuclear medicine at UZ Brussel and head of the molecular imaging research unit at the Vrije Universiteit Brussel (VUB) in Belgium. In 2014 he co-founded the company Camel-IDS NV that is developing a pipeline of radio-immuno therapeutics where he is CSO. He obtained his medical degree in 1998 and started his research activities in combination with a residency program in nuclear medicine. His current research is focused on the development and clinical translation of molecular imaging probes and targeted radionuclide therapies for the detection and treatment of cancer.
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Collaborations and top research areas from the last five years
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ANI437: Understanding tumour biology and microenvironment: from Translational Research to Personalised Cancer Care with PET/CT
Lahoutte, T. (Administrative Promotor) & De Mey, L. (PI (Promotor, Principal Investigator))
1/10/25 → 30/09/26
Project: Fundamental
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IOF3036: INTEGRAL - Integrating a multimodal approach to address current challenges in immunotherapy
Van Ginderachter, J. (Administrative Promotor), Laoui, D. (CoI (Co-Promotor)), Movahedi, K. (CoI (Co-Promotor)), Hadadi, E. (CoI (Co-Promotor)), Stijlemans, B. (CoI (Co-Promotor)), Raes, G. (CoI (Co-Promotor)), Devoogdt, N. (CoI (Co-Promotor)), Lahoutte, T. (CoI (Co-Promotor)), De Groof, T. (CoI (Co-Promotor)), Goyvaerts, C. (CoI (Co-Promotor)), D'Huyvetter, M. (CoI (Co-Promotor)), Debacker, J. (CoI (Co-Promotor)), Breckpot, K. (CoI (Co-Promotor)), Franceschini, L. (CoI (Co-Promotor)), Raes, G. (Mandate) & Revets, H. (Mandate)
1/01/25 → 31/12/29
Project: Applied
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OZR4192: Bilateral cooperation within the framework of a joint doctoral project: benchfee for joint PhD VUB - UC Louvain, DE MEY Lynn
Lahoutte, T. (Administrative Promotor)
18/09/23 → 30/09/27
Project: Fundamental
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FWOIRI9: Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE).
Lahoutte, T. (Administrative Promotor)
1/01/23 → 31/12/26
Project: Fundamental
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SRP83: SRP-Onderzoekszwaartepunt: ITAREG: Molecular Imaging and TArgeting of immunoREGulatory cells in Inflammatory diseases and cancer
Van Ginderachter, J. (Administrative Promotor), Lahoutte, T. (CoI (Co-Promotor)), Lahoutte, T. (Administrative Promotor), Van Ginderachter, J. (Co-Promotor), Devoogdt, N. (Co-Promotor), Raes, G. (Collaborator), Stijlemans, B. (Collaborator), Vincke, C. (Collaborator) & De Groof, T. (Collaborator)
1/11/22 → 31/10/27
Project: Fundamental
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Alphavision: 12 points go to… Astatine-211
Raes, L., Sevenois, M., Bourgeois, S., Bracke, A., De Mey, L., Everaert, H. & Lahoutte, T., 8 Feb 2025.Research output: Unpublished contribution to conference › Unpublished abstract
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Efficient α and β- radionuclide therapy targeting fibroblast activation protein-α in an aggressive preclinical mouse tumour model
Ceuppens, H., Pombo Antunes, A. R., Navarro, L., Ertveldt, T., Berdal, M., Nagachinta, S., De Ridder, K., Lahoutte, T., Keyaerts, M., Devoogdt, N., Goyvaerts, C., D'Huyvetter, M. & Breckpot, K., Jan 2025, In: European Journal of Nuclear Medicine and Molecular Imaging. 52, 2, p. 444-457 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)10 Downloads (Pure) -
Immune modulation following α and β- radionuclide therapy targeting fibroblast activation protein-α in a preclinical tumor model
Ceuppens, H., De Ridder, K., Ertveldt, T., Zeven, K., de Mey, W., Pombo Antunes, A. R., Navarro, L., Dumauthioz, N., Lahoutte, T., Debacker, J., Devoogdt, N., Keyaerts, M., D'Huyvetter, M., Goyvaerts, C. & Breckpot, K., 1 Dec 2025, In: Oncoimmunology. 14, 1, 16 p., 2540054.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)2 Downloads (Pure) -
Preclinical synergistic effects when combining a radiolabelled HER2-targeting single domain antibody with PARP inhibitor Olaparib
Dewulf, J., Navarro, L., Dumauthioz, N., Berdal, M., Nagachinta, S., Gaspariunaite, V., Pombo Antunes, A. R., Lahoutte, T., Massa, S., Devoogdt, N. & D'Huyvetter, M., 13 Dec 2025, In: Journal of Translational Medicine. 24, 13 p., 83.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
Radiolabelled antibody fragments for use in treating cancer
Lahoutte, T. (Inventor), D'Huyvetter, M. (Inventor), De Vos, J. (Inventor) & Devoogdt, N. (Inventor), 2025, Patent No. US12440586B2Research output: Patent
Prizes
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Professor Roger Van Geen Award
Lahoutte, T. (Recipient), Nov 2014
Prize: Prize (including medals and awards)
Activities
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PET/CT imaging of high mannose receptor expressing macrophages with [68Ga]Ga-NOTA -Anti-MMR-VHH2: an overview of the clinical results
De Mey, L. (Speaker), Bourgeois, S. (Contributor), Bracke, A. (Contributor), Gondry, O. (Contributor), Everaert, H. (Contributor), Goethals, L. (Contributor), Debacker, J. (Contributor), Keyaerts, M. (Contributor), Devoogdt, N. (Contributor), Raes, L. (Contributor), Caveliers, V. (Contributor), Van den Block, S. (Contributor), Vaneycken, I. (Contributor), Cousaert, J. (Contributor), De Beule, N. (Contributor), Kerselaers, L. A. A. (Contributor), Forsyth, R. (Contributor), Locy, H. (Contributor) & Lahoutte, T. (Contributor)
11 Oct 2024Activity: Talk or presentation › Talk or presentation at a conference
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PET/CT imaging of high mannose receptor expressing macrophages: first clinical results in cancer and inflammatory disease
De Mey, L. (Speaker), Gondry, O. (Contributor), Bracke, A. (Contributor), Bourgeois, S. (Contributor), Everaert, H. (Contributor), Goethals, L. (Contributor), Raes, L. (Contributor), Gebruers, J. (Contributor), Waelput, W. (Contributor), Caveliers, V. (Contributor), Debacker, J. (Contributor), Devoogdt, N. (Contributor), Dierick, H. (Contributor), Cousaert, J. (Contributor), De Beule, N. (Contributor), Kerselaers, L. A. A. (Contributor), Keyaerts, M. (Contributor) & Lahoutte, T. (Contributor)
12 Mar 2024Activity: Talk or presentation › Talk or presentation at a conference
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Fully automated production of [18F]FB-labeled single-domain antibodies: the immune-checkpoint TIGIT for PET imaging
Dierick, H. (Speaker), Zeven, K. (Contributor), Navarro, L. (Contributor), Lahoutte, T. (Contributor), Devoogdt, N. (Contributor), Caveliers, V. (Contributor) & Bridoux, J. (Contributor)
18 Apr 2024 → 21 Apr 2024Activity: Talk or presentation › Talk or presentation at a conference
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PET/CT imaging with [68Ga]Ga-NOTA-anti-HER2-VHH1 in cancer patients with potential HER2 expression: first clinical results.
De Mey, L. (Speaker), Gondry, O. (Contributor), Bourgeois, S. (Contributor), Bracke, A. (Contributor), Everaert, H. (Contributor), Goethals, L. (Contributor), Raes, L. (Contributor), Caveliers, V. (Contributor), Van den Block, S. (Contributor), Joris, S. (Contributor), de Haar-Holleman, A. (Contributor), Fontaine, C. (Contributor), Devoogdt, N. (Contributor), Dierick, H. (Contributor), Cousaert, J. (Contributor), Lahoutte, T. (Contributor) & Keyaerts, M. (Contributor)
22 Oct 2024Activity: Talk or presentation › Talk or presentation at a conference
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PET/CT imaging with [68Ga]Ga-NOTA-anti-MMR-VHH2 in patients with NSCLC: Interim results of the MAGMA trial
De Mey, L. (Speaker), Bourgeois, S. (Contributor), Bracke, A. (Contributor), Everaert, H. (Contributor), Goethals, L. (Contributor), Gondry, O. (Contributor), Debacker, J. (Contributor), Keyaerts, M. (Contributor), Devoogdt, N. (Contributor), Forsyth, R. (Contributor), Locy, H. (Contributor), Raes, L. (Contributor), Caveliers, V. (Contributor), Van den Block, S. (Contributor), Vaneycken, I. (Contributor), Cousaert, J. (Contributor) & Lahoutte, T. (Contributor)
11 Oct 2024Activity: Talk or presentation › Talk or presentation at a conference
Press/Media
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Camel blood to fight cancer? This VUB spin-off is getting amazing results
Lahoutte, T., Devoogdt, N., D'Huyvetter, M., De Vos, J. & Mebis, C.
17/11/17
1 Media contribution
Press/Media: Research
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Kanker bestrijden met elektrische fietsjes in het bloed
Lahoutte, T., Devenyns, R., Devoogdt, N., D'Huyvetter, M., De Vos, J. & Mebis, C.
17/10/17
1 Media contribution
Press/Media: Research
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Lama-antistoffen in strijd tegen kanker
Lahoutte, T., Devoogdt, N., D'Huyvetter, M., De Vos, J. & Mebis, C.
30/03/17
1 Media contribution
Press/Media: Research
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Toelichting in het kader van Google X: Ontwikkeling van nanopartikels als diagnostische tool bij kankerbestrijding
29/10/14
1 Media contribution
Press/Media: Other
Thesis
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CAMEL-KIT: Single-step labeling of single-domain antibody fragments with 68Ga for PET imaging
Baudhuin, H. V. ((PhD) Student) & Lahoutte, T. ((PhD) Student), Xavier, C. (Promotor), 2021Student thesis: Doctoral Thesis
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Development of a circulating tumor cell model in mice
Vandereycken, J. ((PhD) Student), Lahoutte, T. (Promotor), Goethals, L. (Co-promotor) & Keyaerts, M. (Jury), 10 Jun 2015Student thesis: Master's Thesis