Projects per year
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Collaborations and top research areas from the last five years
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AIIFUND150: Exploring the role of iron in enhancing the maturation, function, and survival of pancreatic beta cells
Staels, W. (Administrative Promotor)
1/04/25 → 31/03/26
Project: Fundamental
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FWOAL1158: Dissecting the role of Neurogenin3 in delta cell development and beta cell regeneration.
Staels, W. (Administrative Promotor)
1/01/25 → 31/12/28
Project: Fundamental
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FWOTM1255: MACBETh: Uncovering the role of MACrophages in BETa cell (re)generation.
Willems, L. (Mandate), De Leu, N. (Administrative Promotor), Staels, W. (CoI (Co-Promotor)) & Van Ginderachter, J. (CoI (Co-Promotor))
1/11/24 → 31/10/28
Project: Fundamental
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HERC66: 3D-CELLMAP: Unveiling complex cellular interactions in tissues through 3D super-resolution protein multiplex imaging
Movahedi, K. (Administrative Promotor), Rooman, I. (CoI (Co-Promotor)), Sermon, K. (CoI (Co-Promotor)), De Bundel, D. (CoI (Co-Promotor)), Fioravanti, A. (CoI (Co-Promotor)), Staels, W. (CoI (Co-Promotor)), Magez, S. (CoI (Co-Promotor)), Breckpot, K. (CoI (Co-Promotor)), De Kock, J. (CoI (Co-Promotor)), Laoui, D. (CoI (Co-Promotor)), Goyvaerts, C. (CoI (Co-Promotor)), Smolders, I. (CoI (Co-Promotor)), Van Ginderachter, J. (CoI (Co-Promotor)), Marcelino Rodrigues, R. (CoI (Co-Promotor)), De Leu, N. (CoI (Co-Promotor)), van Grunsven, L. (CoI (Co-Promotor)), Hernot, S. (CoI (Co-Promotor)), Peeters, E. (CoI (Co-Promotor)), Vanhaecke, T. (CoI (Co-Promotor)), De Veirman, K. (CoI (Co-Promotor)), Ruytinx, J. (CoI (Co-Promotor)), Van Schependom, J. (CoI (Co-Promotor)), Kortekaas, I. (CoI (Co-Promotor)) & Goossens, E. (CoI (Co-Promotor))
1/05/24 → 31/05/28
Project: Fundamental
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AIIFUND117: VASC-ENHANCE: Exploiting Vascular Signals for Enhanced Maturation of iPSC-derived Beta-Like Cells
Staels, W. (Administrative Promotor)
1/02/24 → 31/01/29
Project: Fundamental
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A case of JAGN1 mutation presenting with atypical diabetes and immunodeficiency
De Cuyper, C., Staels, W., Daelemans, S., Vanbesien, J., Nauwynck, E. & Gies, I., 21 Jul 2025, In: Journal of pediatric endocrinology & metabolism. 38, 11, p. 1217-1223 7 p.Research output: Contribution to journal › Article › peer-review
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A new postnatal role for Neurogenic3 in ∂-cells
Coenen, S., van den Ameele, J. (Contributor), Kellens, Y. (Contributor), Pierreux, J. (Contributor), Van Mulders, A. (Contributor), Degroote, L. (Contributor), Bourgeois, S. (Contributor), Willems, L. (Contributor), Heremans, Y. (Contributor), De Leu, N. (Contributor) & Staels, W. (Contributor), 22 Oct 2025, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Atypical complications and co-morbidities of type 1 diabetes in young adults
James, S., Barber, R., Forster, J., Sawatsky, L., Berry, S., James, O., Abel, K., Trigg, C., Donaghue, K. C., Craig, M. E., Saiyed, M., Salis, S. S., Wood, J. & Staels, W., Nov 2025, In: Journal of Diabetes and its Complications. 39, 11, 9 p., 109158.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Biomarkers of iron status and inflammation in Belgian children with overweight and obesity
De Wolf, A. C., De Schepper, J., Nauwynck, E., Vanbesien, J., Huysentruyt, K., Bravo, S., De Geyter, D., Anckaert, E., Gies, I. & Staels, W., 13 May 2025, In: Endocrine Abstracts. 110, p. 857-858 2 p., EP938.Research output: Contribution to journal › Meeting abstract (Journal)
Open Access -
Combination therapy of low-dose anti-CD3 with GLP1-E2 delays and reduces type 1 diabetes onset in non-obese diabetic mice
Degroote, L., Bourgeois, S. (Contributor), Van Mulders, A. (Contributor), Pierreux, J. (Contributor), Coenen, S. (Contributor), Willems, L. (Contributor), Heremans, Y. (Contributor), Staels, W. (Contributor) & De Leu, N. (Contributor), 22 Oct 2025, (Unpublished).Research output: Unpublished contribution to conference › Unpublished abstract
Datasets
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Comprehensive alpha, beta, and delta cell transcriptomics reveal an association of cellular aging with MHC class I upregulation
Staels, W. (Creator), NCBI Gene Expression Omnibus, 27 Jun 2024
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE269616
Dataset
Prizes
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File
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Young Investigator Award - European Society for Pediatric Endocrinology
Staels, W. (Recipient), 2021
Prize: Prize (including medals and awards)
Activities
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Combination therapy of low-dose anti-CD3 with GLP1-E2 delays and reduces type 1 diabetes in non-obese diabetic mice
Degroote, L. (Speaker), Bourgeois, S. (Contributor), Van Mulders, A. (Contributor), Pierreux, J. (Contributor), Willems, L. (Contributor), Coenen, S. (Contributor), Heremans, Y. (Contributor), Staels, W. (Contributor) & De Leu, N. (Contributor)
22 Oct 2025Activity: Talk or presentation › Talk or presentation at a conference
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Hot topic in type 1 diabetes: time for early screening strategies?
Staels, W. (Speaker)
14 Mar 2025Activity: Talk or presentation › Talk or presentation at a conference
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Fall 2025 Beta Cell Replacement Consortium Virtual Meeting
Staels, W. (Speaker)
13 Nov 2025Activity: Talk or presentation › Talk or presentation at a workshop/seminar
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Iron deficiency induces maturation-dependent loss of pancreatic β-cells
Van Mulders, A. (Speaker), Willems, L. (Contributor), Coenen, S. (Contributor), Bourgeois, S. (Contributor), Heremans, Y. (Contributor), Degroote, L. (Contributor), Pierreux, J. (Contributor), De Leu, N. (Contributor) & Staels, W. (Contributor)
25 Oct 2025Activity: Talk or presentation › Talk or presentation at a conference
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Breakthrough T1D - Formerly JDRF
Staels, W. (Participant)
12 Nov 2025 → 13 Nov 2025Activity: Participating in or organising an event › Participation in conference
Thesis
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Glucocorticoid induced adrenal insufficiency evaluated by the low dose corticotropin test in children
Knauf, K. ((PhD) Student), Staels, W. (Promotor) & De Schepper, J. (Promotor), 11 Jun 2024Student thesis: Master's Thesis
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Modulation of Iron Metabolism in Pancreatic Islets
Coenen, S. ((PhD) Student) & Staels, W. (Promotor), Van Mulders, A. (Advisor), 17 Jun 2022Student thesis: Master's Thesis
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Modulation of VEGA-A signaling by beta cells during pregnancy and islet transplantation
Staels, W. ((PhD) Student), Heimberg, H. (Promotor), Cools, M. (Promotor), De Leu, N. (Co-promotor), van Grunsven, L. A. (Jury), Rooman, I. (Jury), Vleminckx, K. (Jury), Ferrer, J. (Jury) & Callaerts, P. (Jury), Heimberg, H. (Promotor), Cools, M. (Promotor), De Leu, N. (Co-promotor), Van Grunsven, L. A. (Jury), Rooman, I. (Jury), Vleminckx, K. (Jury), Ferrer, J. (Jury) & Callaerts, P. (Jury), 30 May 2018Student thesis: Doctoral Thesis
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Recovery from induced intra-islet hypovascularization promotes beta cell proliferation
Hamdaoui, W. ((PhD) Student), Heimberg, H. (Promotor) & Staels, W. (Advisor), 2017Student thesis: Master's Thesis