Projects per year
Personal profile
Expertise
Structural Bioinformatics and computational biology
- Prediction of biophysical characteristics of proteins from their sequence
- Effect of amino acid variants on proteins and organisms
Computational aspects of Nuclear Magnetic Resonance (NMR)
- Statistical analysis of NMR data in relation to protein structure
- Structure determination of proteins from experimental NMR data
Education/Academic qualification
Chemistry, Ph.D., Ghent University
1 Dec 1992 → 19 Dec 1996
Award Date: 19 Dec 1996
External positions
VUB director, Interuniversity Institute of Bioinformatics in Brussels
Apr 2014 → …
Maitre d'enseignement, Université libre de Bruxelles
2011 → …
Scientific officer (NMR), European Bioinformatics Institute
1 Oct 2001 → 30 Sep 2010
Research Fellow, Biotechnology Research Institute, National Research Council, Montreal
1 Jan 2000 → 31 Aug 2001
Postdoctoral researcher, Université libre de Bruxelles
1 Jan 1999 → 31 Dec 1999
Postdoctoral researcher, Biotechnology Research Institute, National Research Council, Montreal
1 Jan 1997 → 31 Dec 1998
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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OZR4184: OZR Ad hoc financiering: ELIXIR Infrastructure for Data and Services to strengthen Life-Sciences Research in Flanders.
1/01/23 → 31/12/26
Project: Fundamental
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FWOIRI14: ELIXIR Infrastructure for Data and Services to strengthen Life-Sciences Research in Flanders.
1/01/23 → 31/12/26
Project: Fundamental
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FWOSB130: Understanding proteins with dynamic behavior from a biophysical angle; application to categorise and design novel (chimeric) GPCRs
Vranken, W., Steyaert, J. & Crauwels, C.
1/11/22 → 31/10/26
Project: Fundamental
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SRP91: SRP-Groeifinanciering: Synthetic biology for the development of microbial cell factories
Peeters, E., Vranken, W. & de Buyl, S.
1/10/22 → 30/09/27
Project: Fundamental
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VLAOO25: O&O Project: ConfoLeGo: a platform towards undruggable GPCRs
1/07/22 → 30/06/25
Project: Applied
Research output
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Deciphering the RRM-RNA recognition code: A computational analysis
Roca Martinez, J., Dhondge, H. B., Sattler, M. & Vranken, W., 23 Jan 2023, In: PLoS Computational Biology. 19, 1, 24 p., e1010859.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)6 Downloads (Pure) -
Deep mutational scanning of essential bacterial proteins can guide antibiotic development
Dewachter, L., Brooks, A. N., Noon, K., Cialek, C., Clark-ElSayed, A., Schalck, T., Krishnamurthy, N., Versées, W., Vranken, W. & Michiels, J., 16 Jan 2023, In: Nature Communications. 14, 1, 16 p., 241.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)39 Downloads (Pure) -
Design of novel chimeric GPCRs: Identification of equivalent regions at the sequence, structural and biophysical level
Crauwels, C. & Vranken, W., 2 Aug 2023, (Unpublished).Research output: Unpublished contribution to conference › Poster
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Evolution of CRISPR-associated endonucleases as inferred from resurrected proteins
Alonso-Lerma, B., Jabalera, Y., Samperio, S., Morin, M., Fernandez, A., Hille, L. T., Silverstein, R. A., Quesada-Ganuza, A., Reifs, A., Fernández-Peñalver, S., Benitez, Y., Soletto, L., Gavira, J. A., Diaz, A., Vranken, W., Sanchez-Mejias, A., Güell, M., Mojica, F. J. M., Kleinstiver, B. P., Moreno-Pelayo, M. A. & 2 others, , Jan 2023, In: Nature Microbiology. 8, 1, p. 77-90 14 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
A roadmap to scientific software deployment: bio2Byte Tools as a use case
Gavalda Garcia, J., Díaz, A. & Vranken, W., 11 Mar 2022.Research output: Unpublished contribution to conference › Poster
Open Access
Datasets
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Prediction of Conformational Variability for RRM proteins in inter3m data base
Gavalda Garcia, J. (Creator) & Vranken, W. (Supervisor), Zenodo, 14 Feb 2023
DOI: 10.5281/zenodo.7640833, https://doi.org/10.5281/zenodo.7640833
Dataset
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Protein ambiguity
Lazar, T. (Creator), Roca Martinez, J. (Researcher), Pancsa, R. (Creator) & Vranken, W. (Supervisor), Frontiers in Molecular Biosciences, 3 Aug 2022
DOI: 10.3389/fmolb.2022.959956, https://bitbucket.org/bio2byte/protein_ambiguity/src/master/
Dataset
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RRMScorer datasets
Roca Martinez, J. (Creator), Vranken, W. (Supervisor) & Dhondge, H. B. (Data Collector), PLOS Computational Biology, 28 Jun 2022
DOI: 10.1371/journal.pcbi.1010859, https://bitbucket.org/bio2byte/rrmscorer/src/master/Supplementary_information/
Dataset
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Bio2Byte SARS-CoV-2
Kagami, L. P. (Creator), Roca Martinez, J. (Creator), Gavalda Garcia, J. (Creator), Ramasamy, P. (Creator), Feenstra, K. A. (Creator) & Vranken, W. (Supervisor), BMC Molecular and Cell Biology, 7 Dec 2020
DOI: 10.1186/s12860-021-00362-w, https://bio2byte.be/sars2/
Dataset
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ConforMine Molecular Dynamics Data: Conformational Variability, Secondary Structure Propensities and Molecular Dynamics Simulations
Gavalda Garcia, J. (Creator), Roca Martinez, J. (Creator) & Vranken, W. (Supervisor), Zenodo, 2023
DOI: 10.5281/zenodo.7575777, https://doi.org/10.5281/zenodo.7575777
Dataset
Activities
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Department of Bio-engineering Sciences (Organisational unit)
Eveline Peeters (Supervisor), Wim Vranken (Supervisor), Dominique Maes (Chair), Charles Van der Henst (Jury), Geert Angenon (Jury), Kiavash Movahedi (Jury), Sébastien Ferreira-Cerca (Jury) & Louis Droogmans (Jury)
9 Mar 2023Activity: Membership › Member of PhD committee
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Department of Bio-engineering Sciences (Organisational unit)
Wim Vranken (Chair), Eveline Peeters (Jury), Jean-Pierre Hernalsteens (Jury), Jos Ruytinx (Jury), Geert Angenon (Supervisor), Sofie Goormachtig (Jury) & Elizabeth Kairuz Hernández-Díaz (Jury)
15 Jun 2023Activity: Membership › Member of PhD committee
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Netherlands Society on Biomolecular Modelling Fall Meeting
Jose Gavalda Garcia (Organiser), Joel Roca Martinez (Organiser), Charlotte Crauwels (Organiser), Konstantina Tzavella (Organiser) & Wim Vranken (Organiser)
27 Oct 2022Activity: Participating in or organising an event › Participation in conference
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Université libre de Bruxelles (External organisation)
Wim Versées (Jury), François Ancien (Presenter), Wim Vranken (Supervisor), Marianne Rooman (Supervisor) & Ann Nowe (Chair)
14 Jan 2022Activity: Membership › Member of PhD committee
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Vrije Universiteit Amsterdam (External organisation)
Wim Vranken (Examiner)
7 Jan 2021Activity: Membership › Membership of peer-review panel or committee
Thesis
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Identification and characterization of putative transcriptional regulators in archaea
Author: Donvil, L., Peeters, E. & Vranken, W., 10 Sep 2018Supervisor: Orlando, G. (Advisor), de Buyl, S. (Jury) & De Greve, H. (Jury)
Student thesis: Master's Thesis
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Unravelling the microbial ecosystems of food-related brines through a metagenomics approach
Author: Vermote, L., Weckx, S., Peeters, E. & Vranken, W., Jul 2016Student thesis: Master's Thesis