3D4Health : Protection structures for health: Structural biology of therapeutic membrane proteins as a starting point for effective rational drug design.

Project Details

Description

3D4Health will develop and use new tools to study the structural and functional properties of therapeutic membrane proteins (GPCRs and MDRs) and to valorize new IP, new screening approaches and new characterization methodologies for the pharmaceutical industry.
Short title or EU acronym3D4Health
AcronymBRGEOZ132
StatusFinished
Effective start/end date1/06/0831/05/11

Flemish discipline codes

  • Biological sciences

Keywords

  • membrane protein
  • Receptor
  • Applied Biology
  • Structure
  • GPCR
  • Structure of a nanobody-stabilized active state of the b2 adrenoceptor

    Rasmussen, S. G. F., Choi, H-J., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F. S., Kobilka, T. S., Schnapp, A., Konetzki, I., Sunahara, R. K., Gellman, S. H., Pautsch, A., Steyaert, J., Weis, W. I. & Kobilka, B. K., 13 Apr 2011, In : Nature. 469, 7329, p. 175-180 5 p.

    Research output: Contribution to journalArticle

    Open Access
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    1173 Citations (Scopus)
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