-A-CUTE-TOX : Optimisation and pre-validation of an in vitro test strategy for predicting human acute toxicity

Project Details


The aim of A-Cute-Tox is to develop a simple and robust in vitro testing strategy
for prediction of human acute systemic toxicity, which could replace the animal acute toxicity tests used today for regulatory purposes. Our laboratory will investigate the use of IC50 values of chemicals for in vitro cytokine production by human peripheral blood cells.
Effective start/end date1/01/0530/06/10


  • pharmacology

Flemish discipline codes

  • Basic sciences