A microarray besed analysis of the interplay of glucose and incretins as regulators of beta cell gene expression

Pancreatic ß-cells respond to glucose in secreting insulin, this response is amplified by the addition of incretins. The aim of our study is to identify pathways and genes involved in the interplay of incretins (GLP-1, GIP, CCK-A a.o) by microarray experiments on purified rat ß-cells and human purified ß-cells