Ammonia and lactate: differential information on monitoring training load during graded.

Project Details


The blood lactate (La)-workload relationchip assessed during a graded maximal exercise test (GTX) is often used to provide training guidelines to athletes. Glycogen depletion is a condition that is known to influence the La response during a GTX and therefore can bias the interpretation La curves. The purpose of this study is to determine the influence of a glycogen depletion exercise (GDE) onLa and ammonia accumulation (NH3) during GTX. 12 persons will perform a cycle ergometer GXT (3 min. protocol) on two sepperate occasions with a 1-week interval. Using a randomized cross-over design, one of the two GXT's will be preceded by a prolonged GDE untilexhaustion in attempt to deplete muscle and liver glycogen stores. NH3 accumulation, after GDE, is expected to increase more rapidly in the depleted versus control state whereas La accumulation is expected to increas less rapidly in the depleted state. We hypothesize, therefore, that determination of NH3 during a GXT may provide helpful additional information for training recommendations which is not available by La determination alone.
Effective start/end date1/01/9831/12/98

Flemish discipline codes

  • Basic sciences


  • biochemistry
  • medicine