CoDaFlight : Colouring the Dark in Fluorescence Light (EU BONUS OZR)

Abstract The radical vision of CoDaFlight (Colouring the Dark in Fluorescence light) is the development of a next-generation imaging
platform capable of revealing in real-time new and more accurate information related to a patient’s body and its diseases through an
innovative time-domain fluorescence imaging (tdFLI) technology. Real-time imaging of fluorescence lifetime, deep into the patient,
permits the unlocking of rich information, where today’s medical imaging systems remain in the dark. This novel, breakthrough
technology is expected to find in first instance broad applicability during medical surgery, where it will influence intraoperative
decision-making on a per patient basis. The consortium encompasses unique, complementary and multidisciplinary expertise, by
bringing electronic and biomedical engineers, physicists, chemists, medical scientists and medical doctors together. In a
multidisciplinary, holistic approach they allow both parallel and integrated research progression, on semiconductor image sensors,
mathematical algorithms, fluorescent dyes, and biological proof of concepts under medical guidance. CoDaFlight will kickstart a new
biomedical research field, the development of new solutions towards unmet clinical needs and addresses the growing need for safe
diagnostic tools that can interrogate molecular and/or physiological parameters in real-time for immediate feedback during medical
interventions or for continuous health monitoring.