Contributions to faster development and validation of pharmaceutical analytical separation methods : experimental design in method optimization and method validation

Mathematics

1. Experimental design 100%
2. High-performance Liquid Chromatography 65%
3. Robustness 53%
4. Plackett-Burman Design 43%
5. Experiment 38%
6. Supersaturated Design 37%
7. Testing 36%
8. Design 31%
9. PLS Regression 20%
10. Screening Design 19%
11. Optimization 19%
12. Randomization Test 18%
13. Uniform Design 18%
14. Detection Limit 18%
15. Fractional Factorial 18%
16. Interpretation 18%
17. Chemometrics 17%
18. Dyes 17%
19. Warping 17%
20. Interaction Effects 17%
21. Spectroscopy 16%
22. Pharmaceuticals 16%
23. D-optimal Design 16%
24. Ridge Regression 15%
25. Coating 15%
26. Deconvolution 14%
27. Wavelength 14%
28. Quantification 14%
29. Optimization Methods 13%
30. Tolerance 13%
31. Gauge 13%
32. Drugs 13%
33. Influence 9%
34. Evaluation 9%
35. Interaction 9%
36. Strategy 8%