Derivation and characterisation of human embryonic stem cells (hESC) with myotonic dystrophy, DUchennes muscular dystrophy or facioscapulohumeral dystrophy and differentiation of normal and affected hESC to myocytes.

Mateizel, Ileana (Collaborator)
Van Steirteghem, Andre (Co-Promotor)
Leyns, Luc (Co-Promotor)
Liebaers, Ingeborg (Co-Promotor)
Sermon, Karen (Administrative Promotor)

6 Article
1 Meeting abstract (Book)

7 results

2011
Huntington's and myotonic dystrophy hESCs: down-regulated trinucleotide repeat instability and mismatch repair machinery expression upon differentiation
Seriola Petit, A., Spits, C., Hilven, P., Haentjens, P. & Sermon, K., 1 Jan 2011, In: Human Molecular Genetics. 20, p. 176-185 10 p.
Research output: Contribution to journal › Article › peer-review
77 Citations (Scopus)
2008
CTG repeat instability in a human embryonic stem cell line carrying the myotonic dystrophy type 1 mutation.
De Temmerman, N., Seneca, S., Van Steirteghem, A., Haentjens, P., Van Der Elst, J., Liebaers, I. & Sermon, K., Jul 2008, In: Molecular Human Reproduction. 14, July, p. 405-412 13 p.
Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus)
Efficient differentiation of human embryonic stem cells into a homogeneous population of osteoprogenitor-like cells.
Mateizel, I., De Becker, A., Van De Velde, H., De Rycke, M., Van Steirteghem, A., Cornelissen, R., Van Der Elst, J., Liebaers, I., Van Riet, I. & Sermon, K., 19 Mar 2008, In: Reprod Biomed Online. 16, May, p. 741-753 13 p.
Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus)
Patterning of mouse embryonic stem cell-derived pan-mesoderm by Activin A/Nodal and Bmp4 signaling requires fibroblast growth factor activity
Willems, E. & Leyns, L., 2008, In: Differentiation. 76, p. 745-759 15 p.
Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus)
2007

Differentiation of human embryonic stem cells into a homogenous population of mesenchymal-stem-cell-like unipotent progenitors of the osteogenic lineage
Sermon, K., Mateizel, I., De Becker, A., Van De Velde, H., De Rycke, M., Van Steirteghem, A., Van Der Elst, J., Liebaers, I. & Van Riet, I., 17 Jul 2007, 5th ISSCR Annual Meeting Abstract Book. p. 298 1 p. (5th ISSCR Annual Meeting Abstract Book).
Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book)
Epithelial-mesenchymal transition process in humanembryonic stem cells cultured in feeder-free conditions
Ullmann, U., In 'T Veld, P., Gilles, C., Sermon, K., De Rycke, M., Van De Velde, H., Van Steirteghem, A. & Liebaers, I., Jan 2007, In: Molecular Human Reproduction. 13, 1, p. 21-32 12 p.
Research output: Contribution to journal › Article › peer-review
113 Citations (Scopus)
2006
Selection of reference genes in mouse embryos and in differentiating human and mouse ES cells
Willems, E., Mateizel, I., Kemp, C., Cauffman, G., Sermon, K. & Leyns, L., 2006, In: International Journal of Developmental Biology. 50, 7, p. 627-635 9 p.
Research output: Contribution to journal › Article › peer-review
106 Citations (Scopus)