Effects of Prolactin(PRL)on human leukocytes

Project Details


To better understand the role PRL plays in the immune system in men, PRL/PRL-R signalling pathways(JAK/Stat, Ras/MAPKinases)are analyzed. The expression of specific genes such as IRF-1, iNOS, CIS en SOCS will be studied in different leukocyte subpopulations (B and T lymphocytes, granulocytes...)prepared from healthy donors. . The functional properties en the working mechanism of certain SOCS factors will be characterized.
Effective start/end date1/01/0231/12/05


  • cytokines
  • prolactin
  • JAK/Stat
  • signalling pathways
  • leukocytes
  • SOCS
  • prolactine
  • Ras/MAPKinases
  • iNOS
  • IRF-1
  • CIS

Flemish discipline codes

  • Biological sciences