To better understand the role PRL plays in the immune system in men, PRL/PRL-R signalling pathways(JAK/Stat, Ras/MAPKinases)are analyzed. The expression of specific genes such as IRF-1, iNOS, CIS en SOCS will be studied in different leukocyte subpopulations (B and T lymphocytes, granulocytes...)prepared from healthy donors. . The functional properties en the working mechanism of certain SOCS factors will be characterized.
|Effective start/end date||1/01/02 → 31/12/05|
- signalling pathways
Flemish discipline codes
- Biological sciences