Project Details
Description
CHIMERNA aims to develop and
validate a Hydrogel Immune Modulating Therapy (HIT) that can be injected subcutaneously and is a hub for in situ immune cell modification.
validate a Hydrogel Immune Modulating Therapy (HIT) that can be injected subcutaneously and is a hub for in situ immune cell modification.
| Acronym | FWOEUAR2 |
|---|---|
| Status | Active |
| Effective start/end date | 1/01/25 → 31/12/27 |
Keywords
- immune therapy
Flemish discipline codes in use since 2023
- Cancer therapy
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Intratumoral delivery of mRNA for colorectal cancer treatment: opening new immunotherapy horizons
Sigler, A., Autaers, D., Franceschini, L., Breckpot, K. & Van der Jeught, K., 7 May 2025, p. 1. 1 p.Research output: Unpublished contribution to conference › Poster
Open AccessFile2 Downloads (Pure) -
Sequence simplification of antigen coding IVT mRNA allows accelerated synthetic DNA template generation and epitope immunogenicity validation
Esprit, A., Autaers, D., Aernout, I., Lentacker, I., Pascolo, S., Thielemans, K., Breckpot, K. & Franceschini, L., 9 Sept 2025, In: Molecular Therapy Nucleic Acids. 36, 3, 11 p., 102591.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Datasets
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Sequence simplification of antigen coding IVT mRNA allows accelerated synthetic DNA template generation and epitope immunogenicity validation
Breckpot, K. (Creator), Esprit, A. (Creator), Autaers, D. (Creator), Franceschini, L. (Creator), Lentacker, I. (Creator) & Aernout, I. (Creator), VUB Institutional Data Repository, 11 Aug 2025
Dataset
Activities
- 2 Talk or presentation at a conference
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The promise of new modalities: keeping Belgium in the lead
Breckpot, K. (Speaker)
4 Nov 2025Activity: Talk or presentation › Talk or presentation at a conference
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An mRNA as a toolbox for patient-tailored vaccine development.
Breckpot, K. (Speaker)
20 Oct 2025Activity: Talk or presentation › Talk or presentation at a conference