Formation of Functional Beta Cells from Pancreatic Progenitor Cells

Project Details


Our project investigates whether a functional beta cell mass can be formed by pancreatic progenitors derived from human embryonic stem cells and shown to form insulin producing cells when implanted in immune-deficient mice. This study not only assesses the therapeutic potential of huESC-PP-cells. It can also clarify the formation of a functional beta cell mass in the normal pancreas, or failure to do so in diabetes. It can lead to procedures that isolate and expand pancreatic progenitors from donor organs.
Effective start/end date1/10/1130/09/15


  • Cell Therapy
  • Prevention
  • Transplantation
  • Diagnostic Tests
  • Immunology
  • Cell Death and Survival
  • Islet Cell Pathology
  • Islet Cell Biology
  • Beta Cell Transplantation
  • Diabetes

Flemish discipline codes in use since 2023

  • Biological sciences
  • Basic sciences


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