Project Details
Description
Our project investigates whether a functional beta cell mass can be formed by pancreatic progenitors derived from human embryonic stem cells and shown to form insulin producing cells when implanted in immune-deficient mice. This study not only assesses the therapeutic potential of huESC-PP-cells. It can also clarify the formation of a functional beta cell mass in the normal pancreas, or failure to do so in diabetes. It can lead to procedures that isolate and expand pancreatic progenitors from donor organs.
Acronym | FWOTM606 |
---|---|
Status | Finished |
Effective start/end date | 1/10/11 → 30/09/15 |
Keywords
- Cell Therapy
- Prevention
- Transplantation
- Diagnostic Tests
- Immunology
- Cell Death and Survival
- Islet Cell Pathology
- Islet Cell Biology
- Beta Cell Transplantation
- Diabetes
Flemish discipline codes
- Basic sciences
- Biological sciences