Project Details
Description
Our project investigates whether a functional beta cell mass can be formed by pancreatic progenitors derived from human embryonic stem cells and shown to form insulin producing cells when implanted in immune-deficient mice. This study not only assesses the therapeutic potential of huESC-PP-cells. It can also clarify the formation of a functional beta cell mass in the normal pancreas, or failure to do so in diabetes. It can lead to procedures that isolate and expand pancreatic progenitors from donor organs.
| Acronym | FWOTM606 |
|---|---|
| Status | Finished |
| Effective start/end date | 1/10/11 → 30/09/15 |
Keywords
- Cell Therapy
- Prevention
- Transplantation
- Diagnostic Tests
- Immunology
- Cell Death and Survival
- Islet Cell Pathology
- Islet Cell Biology
- Beta Cell Transplantation
- Diabetes
Flemish discipline codes in use since 2023
- Biological sciences
- Basic sciences
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