Research output per year
Research output per year
Project Details
Description
Objective
Identification and regulation of beta cell phenotypeswith therapeutic potential.
Finding should help
-assess functional beta cell mass in isolated preparations
-select donor cells and perform quality control tests on beta cell grafts
-generate and preserve beta cells in the laboratory
-histo(patho)logic analysis of beta cells in the human pancreas
-define condotions for composition and preservation of a functional beta cell mass.
Specific aims
I. Characterization of phenotypes in the life cycle of beta cells
II Phenotyping human beta cells
III Regulation of beta cell phenotypes by nutrients and peptides
IV Comparison of primary beta cells with cells generated from stem/precursor cells and from transdifferentiated cells.
Identification and regulation of beta cell phenotypeswith therapeutic potential.
Finding should help
-assess functional beta cell mass in isolated preparations
-select donor cells and perform quality control tests on beta cell grafts
-generate and preserve beta cells in the laboratory
-histo(patho)logic analysis of beta cells in the human pancreas
-define condotions for composition and preservation of a functional beta cell mass.
Specific aims
I. Characterization of phenotypes in the life cycle of beta cells
II Phenotyping human beta cells
III Regulation of beta cell phenotypes by nutrients and peptides
IV Comparison of primary beta cells with cells generated from stem/precursor cells and from transdifferentiated cells.
| Acronym | FWOAL409 |
|---|---|
| Status | Finished |
| Effective start/end date | 1/01/07 → 31/12/10 |
Keywords
- medicine
Flemish discipline codes in use since 2023
- Endocrinology
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Research output
- 1 Article
-
Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity
Hellemans, K., Kerckhofs, K., Hannaert, J., Martens, G., Van Veldhoven, P. & Pipeleers, D., 2007, In: The FEBS Journal. 274, p. 6094-6105 10 p.Research output: Contribution to journal › Article › peer-review
47 Citations (Scopus)
Activities
- 2 Membership of external research organisation
-
Unknown (External organisation)
Geert Martens (Member)
2007 → …Activity: Membership › Membership of external research organisation
-
Unknown (External organisation)
Daniel Pipeleers (Member)
2007 → …Activity: Membership › Membership of external research organisation