Junior Grant Award Agreement: Unraveling the balance of tolerance and immunogenicity of multiple myeloma cells.

Cancer cells are known for their ability to evade the immune system. Important in this process is the ability of cancer cells to prevent the activation of the immune system which has been insufficiently studied in multiple myeloma. In this project, we will investigate how multiple myeloma cells prevent the stimulation of two important immune cell types that should ‘eat’ myeloma cells or parts or myeloma cells in order to stimulate the immune system. The obtained results should be helpful to develop new treatments to stimulate these immune cells and improve wellbeing of patients.