Molecular dialogue between parasite and hosts : the trypansome model

  • De Baetselier, Patrick (Administrative Promotor)
  • Coosemans, Marc (Co-Promotor)
  • Pays, Etienne (Coördinator)
  • European Partner(s), . (Co-Promotor)
  • European Partner(s), - (Collaborator)
  • Michels, Paul (Co-Promotor)

Project Details

Description

To study the molecular mechanisms used by parasites to undergo developmental transformations and to adapt to their hosts by using the African trypanosomes (prototype Trypanosoma brucei) as model organisms. This project can be divided into two parts:

Studies on the parasite
Endocytosis of host macromolecules (TCD, ULB)
Cell signalling (LMUM, ULB)
Controls of gene expression (ULB)
Metabolic changes during the parasite life-cycle
Study of host-parasite interactions
Mechanisms underlying pathology in mammalian hosts (VUB)
Macrophage - trypanosome interactions (VUB, ULB)
Tsetse fly - trypanosome interactions (ITG, ULB, VUB)
AcronymDWTC208
StatusFinished
Effective start/end date1/01/0731/03/12

Flemish discipline codes

  • Biological sciences

Keywords

  • biology