Nanobody assisted structural study of ELIC, a prokaryotic GABA-gated ion channel

  • Steyaert, Jan (Administrative Promotor)
  • Ulens, Chris (Coördinator)

Project Details

Description

The recent discovery of ELIC, a bacterial GABA-activated ion channel, opens new opportunities to pursue structural insight into ion channel function. In the current proposal we will take advantage of cutting-edge technologies, including nanobody-assisted crystallography, chemical biology and cysteine-trapping to study three essential aspects of ion channel function.
AcronymFWOAL683
StatusFinished
Effective start/end date1/01/1331/12/16

Flemish discipline codes

  • Biomedical modelling
  • Other biotechnology, bio-engineering and biosystem engineering

Keywords

  • Applied Biology