SBO project with a primary economic finality aimed at the transfer to existing companies : iPSC-based parenchymal and sinusoidal liver cell mimics for DILI and NAFLD studies (iPSC-LiMic)

Project Details


iPSC-LiMic will establish a unique platform in Flanders, and one of the few in Europe, where in iPSC- derived parenchymal hepatocytes as wellas sinusoidal cells (hepatic stellate cells, HSCs; liver sinusoidalendothelial cells, LSECs; and Kupffer cells, KCs) are created from humaniPSC and assembled in 3D cocultures (termed 3D iPS-liver mimics), whichcan be maintained for >20 days in culture
Effective start/end date1/10/2030/09/24

Flemish discipline codes

  • Biostatistics


  • liver mimics
  • biomedicine