SBO project with a primary economic finality aimed at the transfer to existing companies : iPSC-based parenchymal and sinusoidal liver cell mimics for DILI and NAFLD studies (iPSC-LiMic)

Project Details

Description

iPSC-LiMic will establish a unique platform in Flanders, and one of thefew in Europe, wherein iPSC- derived parenchymal hepatocytes as wellas sinusoidal cells (hepatic stellate cells, HSCs; liver sinusoidalendothelial cells, LSECs; and Kupffer cells, KCs) are created from humaniPSC and assembled in 3D cocultures (termed 3D iPS-liver mimics), whichcan be maintained for >20 days in culture.
AcronymFWOSBO39
StatusActive
Effective start/end date1/10/2030/09/24

Flemish discipline codes

  • Biostatistics

Keywords

  • liver mimics
  • biomedicine