A bottom up approach to non-invasive glucose measurements

Research output: Chapter in Book/Report/Conference proceedingMeeting abstract (Book)


There are 150 millions of Diabetic Patients around the world and the World Health Organization expects 300 milion by 2025. The intensive insulin therapy (iit) improves the conditions and prognostic of the patient but increases the risk of hypoglycaemic events [1]. Therefore, close monitoring of glucose is highly recommended such that the level of glucose can be kepts as close as possible into the normal range. Actually the standard for home monitoring is based on a finger-prick blood samples procedure which is time-consuming, painful and offers only intermittent samples. Developing a non-invasive glucose system (NI-GS) would improve the glucose monitoring as required by the iit. Earlier attempts to generat a similar application have failed. They have not achieved the technical or clinical requirements, due to the lack of a solid background on the measurement concept, poor use of information, or have not taken into account external factors that could affect the sensor behaviour. [2] [3]. This project will focus on the development of a NI-GS based on bio-impedance measurements, which are well-known in electrical engineering. The impedance value at the frequencies where glucose molecules resonate is proportional to the glucose level in the blood. This knowledge combined with strong signal analysis will generate a realistic and workable glucose measurement concept. The development will be split up into two complementary stages: 1. A well-founded measurement technique and 2. The hardware development.
Original languageEnglish
Title of host publicationPresentation of plenary lecture at 30th Benelux Meeting on Systems and Control, Lommel, Belgium, March 15-17, 2011
Publication statusPublished - 15 Mar 2011
EventUnknown -
Duration: 15 Mar 2011 → …


Period15/03/11 → …


  • non-invasive glucose measurements


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