A red orange extract modulates the vascular response to a recreational dive: a pilot study on the effect of anthocyanins on the physiological consequences of scuba diving

C Balestra, F Cimino, S Theunissen, T Snoeck, S Provyn, R Canali, A Bonina, F Virgili

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Nutritional antioxidants have been proposed as an expedient strategy to counter the potentially deleterious effects of scuba diving on endothelial function, flow-mediated dilation (FMD) and heart function. Sixteen volunteers performing a single standard dive (20 min at 33 m) according to US Navy diving procedures were randomly assigned to two groups: one was administered with two doses of 200 mg of an anthocyanins (AC)-rich extract from red oranges, 12 and 4 h before diving. Anthocyanins supplementation significantly modulated the effects of diving on haematocrit, body water distribution and FMD. AC administration significantly reduces the potentially harmful endothelial effects of a recreational single dive. The lack of any significant effect on the most common markers of plasma antioxidant capacity suggests that the mechanism underlying this protective activity is independent of the putative antioxidant effect of AC and possibly involves cellular signalling modulation of the response to high oxygen.

Original languageEnglish
Pages (from-to)2101-2106
Number of pages6
JournalNatural Product Research
Volume30
Issue number18
Early online date7 Nov 2015
DOIs
Publication statusPublished - Sep 2016

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