A survey on the applications of implantable micropump systems in drug delivery

Ali Mahnama, Ghader Ghorbaniasl, Ahmad Nourbakhsh

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Systemic drug delivery is the most prevalent form of the drug administration; but it is not possible to extend this approach to all of diseases. In the traditional approaches of drug delivery, the drug spreads through whole of body and this could cause severe side effects in the healthy parts. In addition, in some parts of our body like the eye, ear and brain, there are biological barriers against drug penetration which made drug delivery to these organs as a challenging work. Micropumps are one of the MEMS based devices with great capabilities in controlled drug administration. The most prevalent application of micropumps in drug delivery is known as continuous subcutaneous insulin infusion (CSII) for diabetic patients; but our study showed that there are some other ongoing investigations to extend application of micropumps in new treatment methods for some incurred diseases.
Original languageEnglish
Pages (from-to)123-131
Number of pages9
JournalCurrent Drug Delivery
Volume11
Issue number1
Publication statusPublished - 1 Feb 2014

Keywords

  • micropump
  • drug delivery

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