A systematic review on costs and cost-effectiveness of screening and prevention of type 2 diabetes in women with prior gestational diabetes: Exploring uncharted territory

Amber Werbrouck, Masja Schmidt, Koen Putman, Katrien Benhalima, Nick Verhaeghe, Lieven Annemans, Steven Simoens

Research output: Contribution to journalScientific review

8 Citations (Scopus)

Abstract

AIMS: Women with gestational diabetes mellitus (GDM) are more likely to develop type 2 diabetes mellitus (T2DM) as compared to women with normoglycemic pregnancies. This study aims to explore the literature on cost(-effectiveness) of screening and prevention of T2DM in women with prior GDM.

METHODS: Five databases were systematically searched, inclusion criteria were: (1) women with (prior) GDM; (2) post-partum screening or prevention of T2DM; and (3) health-economic evaluations. No year limits were applied. English, Dutch, French or German publications were included. Quality was assessed using the Consensus Health Economic Criteria checklist.

RESULTS: Two cost-effectiveness analyses and two cost analyses were found. One study evaluated nine screening strategies. Three studies evaluated one prevention strategy each: intensive diet and behavioural modification; annual counseling; and an annual dietary consultation. Methodological quality was poor. Perspectives were unclear, time horizons were too short, and no incremental analyses were performed.

CONCLUSION: An oral glucose tolerance test per three years leads to the lowest cost per case detected, and prevention is potentially cost-effective or cost-saving. More health economic evaluations are needed that compare all relevant alternatives, including 'doing nothing'.

Original languageEnglish
Pages (from-to)138-148
Number of pages11
JournalDiabetes Research and Clinical Practice
Volume147
DOIs
Publication statusPublished - 1 Jan 2019

Bibliographical note

Copyright © 2018 Elsevier B.V. All rights reserved.

Keywords

  • Gestational diabetes mellitus
  • Health economics
  • Prevention
  • Systematic review
  • Type 2 diabetes mellitus
  • Pregnancy
  • Mass Screening
  • Diabetes, Gestational/economics
  • Humans
  • Female
  • Cost-Benefit Analysis/methods
  • Diabetes Mellitus, Type 2/pathology

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