Abstract
The present study speculates on the potential gain we can expect of a further leap in pressure by moving from the current 1500 bar to a futuristic 3000 bar as well as reviews the main impediments to be expected when trying to realize such systems. The study focuses on so-called "analytical scale" separations, i.e., separations that are currently carried out in 2.1 mm columns, as this is the current state-of-the-art in ultrahigh-pressure liquid chromatography (UHPLC) instrumentation.
| Original language | English |
|---|---|
| Pages (from-to) | 554-560 |
| Number of pages | 6 |
| Journal | Analytical Chemistry |
| Volume | 92 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 7 Jan 2020 |
Keywords
- Band Broadening Contributions
- Kinetic Performance
- Core-Shell
- MU-M
- Representation Methods
- Temperature-Gradients
- Operating Pressure
- Heat Dissipation
- Practical Method
- Efficiency
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Dive into the research topics of 'Advances and Challenges in Extremely High-Pressure Liquid Chromatography in Current and Future Analytical Scale Column Formats'. Together they form a unique fingerprint.Projects
- 1 Finished
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SRP6: Strategic Research Programme: Exploiting the Advantages of Order and Geometrical Structure for a Greener Chemistry
Desmet, G. (Administrative Promotor), Denayer, J. (Administrative Promotor), Denayer, J. (Co-Promotor), Desmet, G. (Administrative Promotor) & Denayer, J. (Co-Promotor)
1/11/12 → 31/10/22
Project: Fundamental
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