An infant with localized vasoconstriction following topical propranolol exposure for infantile hemangioma

Research output: Contribution to journalArticle

Abstract

We describe a 3-month-old child with an infantile hemangioma on the forehead with a blanched macule provoked by topical treatment with propranolol. This observation demonstrates that topically applied (non-selective) beta-blockers may induce blanched macules at the site of application, a side effect due to peripheral vasoconstriction of blood vessels by non-selective beta-2 blockade. This side effect was linked due to overuse and was reversible. This case illustrates the importance of providing thorough instructions regarding topical propranolol application.

Original languageEnglish
Pages (from-to)263-264
Number of pages2
JournalPediatric Dermatology
Volume38
Issue number1
Early online date4 Dec 2020
DOIs
Publication statusPublished - 1 Jan 2021

Bibliographical note

© 2020 Wiley Periodicals LLC.

Keywords

  • beta-blocker
  • drug reaction
  • infantile hemangioma
  • propranolol
  • timolol

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