An update of luteal phase support in stimulated IVF cycles.

Hm Fatemi, Biljana Popovic-Todorovic, Evangelos Papanikolaou, Patricio Donoso, Paul Devroey

Research output: Contribution to journalArticlepeer-review

149 Citations (Scopus)


Stimulated IVF cycles are associated with luteal phase defect. In order to overcome this, different doses, durations and types of luteal phase support (LPS) have been evaluated. There is still no agreement regarding the optimal supplementation scheme. The aim of this paper is to assess the past and the current clinical practices of luteal supplementation in IVF. The databases of Medline and PubMed were searched to identify relevant publications. LPS with human chorionic gonadotrophin (hCG) [n=262, odds ratio (OR) 2.72 (95%), confidence interval (CI) 1.56-4.90, P
Original languageEnglish
Pages (from-to)581-590
Number of pages10
JournalHuman Reproduction Update
Publication statusPublished - 2007


  • luteal phase support
  • IVF
  • progesterone


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