Anti-macrophage mannose receptor single variable domains for targeting and in vivo imaging of tumor-associated macrophages

Jo Van Ginderachter (Inventor), Patrick De Baetselier (Inventor), Nick Devoogdt (Inventor), Tony Lahoutte (Inventor), Damya Laoui (Inventor), Kiavash Movahedi (Inventor), Geert Raes (Inventor), Steve Schoonooghe (Inventor)

Research output: Patent

Abstract

The disclosure relates to immunoglobulin single variable domains directed against human macrophage mannose receptor (MMR) and their uses in the field of oncology. More specifically, it concerns immunoglobulin single variable domains, including single-domain antibodies (sdAbs), against human MMR and their use in targeting and in vivo imaging of tumor-associated macrophages, with applications in the field of cancer diagnostics and therapeutics and monitoring of the disease.
Original languageEnglish
Patent numberUS9556273
Publication statusPublished - 2017

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