Assessing the biological reactivity of organic compounds on volcanic ash: implications for human health hazard

Ines Tomasek, David E. Damby, Daniele Andronico, Peter Baxter, Imke Boonen, Philippe Claeys, Michael Denison, Claire J. Horwell, Matthieu Kervyn, Ulrich Kueppers, Manolis Romanias, Marc Elskens

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)
132 Downloads (Pure)

Abstract

Exposure to volcanic ash is a long-standing health concern for people living near active volcanoes and in distal urban areas. During transport and deposition, ash is subjected to various physicochemical processes that may change its surface composition and, consequently, bioreactivity. One such process is the interaction with anthropogenic pollutants; however, the potential for adsorbed, deleterious organic compounds to directly impact human health is unknown. We use an in vitro bioanalytical approach to screen for the presence of organic compounds of toxicological concern on ash surfaces and assess their biological potency. These compounds include polycyclic aromatic hydrocarbons (PAHs), polychlorinated dibenzop- dioxins and dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (dlPCBs). Analysis of ash collected in or near urbanised areas at five active volcanoes across the world (Etna, Italy; Fuego, Guatemala; Kelud, Indonesia; Sakurajima, Japan; Tungurahua, Ecuador) using the bioassay inferred the presence of such compounds on all samples. A relatively low response to PCDD/Fs and the absence of a dlPCBs response in the bioassay suggest that the measured activity is dominated by PAHs and PAH-like compounds. This study is the first to demonstrate a biological potency of organic pollutants associated with volcanic ash particles. According to our estimations, they are present in quantities below recommended exposure limits and likely pose a low direct concern for human health.
Original languageEnglish
Article number30
Number of pages11
JournalBulletin of Volcanology
Volume83
Issue number5
DOIs
Publication statusPublished - 8 Apr 2021

Bibliographical note

Funding Information:
We acknowledge Heather Wright (USGS) and Supriyati Andreastuti (CVGHM in Yogyakarta) for providing the Kelud ash sample. We are thankful to Alexa Van Eaton, two anonymous reviewers and associate editor Christopher Gregg for their constructive comments on this manuscript.

Funding Information:
This work was funded by a VUB Strategic Research Programme to PC-ME-MK and was supported by the Research Foundation Flanders grant to ME (FWOKN299). IT, CJH and UK acknowledge the support by the Marie Sk\u0142odowska-Curie Actions Initial Training Network \u2018VERTIGO\u2019, funded through the European Seventh Framework Programme (FP7 2007\u20132013) under Grant Agreement number 607905. The H1L7.5 cell line was developed by the University of California-Davis (USA) with funding from a Superfund Research Programme grant (ES04699) from the National Institute of Environmental Health Sciences.

Publisher Copyright:
© 2021, The Author(s).

Keywords

  • volcanic ash
  • human health
  • organic compounds
  • CALUX bioassay
  • Urban pollutant
  • Hazard assessment

Fingerprint

Dive into the research topics of 'Assessing the biological reactivity of organic compounds on volcanic ash: implications for human health hazard'. Together they form a unique fingerprint.

Cite this