Biomonitorization of metal ions in the serum of Iranian patients treated with fixed orthodontic appliances in comparison with controls in eastern Iran

Mahdjoube Goldani Moghadam, Reyhane Hoshyar, Marcin Mikulewicz, Katarzyna Chojnacka, Geir Bjørklund, Joeri J Pen, Nammam Ali Azadi, Maghdad Pirsaheb, Meysam Dashtaki, Borhan Mansouri

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The present study aimed to assess the level of metal ions [chromium (Cr), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni), and zinc (Zn)] in the serum of patients with fixed orthodontic appliances. One hundred samples (32 males, 68 females) were collected from patients undergoing fixed orthodontic treatment for different periods. A reference (control) group (24 males, 16 females) who had no appliances was used to properly evaluate the changes in the level of these elements in orthodontic appliance users. The element concentrations were measured using inductively coupled plasma mass spectrometry (ICP-MS). Higher concentrations of metal ions (except for Cr) were found in the serum of the orthodontic group. Bivariate scatter plot showed a highly significant (p < 0.001) correlation between Ni and other elements. The duration of orthodontic treatment increased significantly the Ni levels whereas the bracket type was found to have no significant impact on altering the concentration level of metal ions. The results of the SEM-EDS showed a high variation in the level of metal ions in the brackets and wires. In conclusion, fixed orthodontic appliances increased serum levels of Ni, Zn, Mn, Fe, and Cu but did not change Cr levels.

Original languageEnglish
Pages (from-to)33373-33386
Number of pages14
JournalEnvironmental Science and Pollution Research
Volume26
Issue number32
DOIs
Publication statusPublished - 1 Nov 2019

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