C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo

Timo-Daniel Voss; Jan Lewerenz; Frederic Appelt; Richard Klaus; Sato Hideyo; Giulia Albertini; Ilse Smolders; Ann Massie

C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo

Timo-Daniel Voss, Jan Lewerenz, Frederic Appelt, Richard Klaus, Sato Hideyo, Giulia Albertini, Ilse Smolders, Ann Massie

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book) › Research

Abstract

Inflammatory stimuli upregulate system xc- in vivo and in vitro. This is mediated by increased transcription of xCT, the specific subunit of system xc-. Counterintuitively, NFκB might rather represent an inhibitory feedback loop in the inflammatory induction of system xc-downstream of inflammatory pathways

Original language	English
Title of host publication	Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018
Number of pages	1
Publication status	Published - 2018
Event	11th FENS Forum of Neuroscience - Berlin, Germany Duration: 7 Jul 2018 → 11 Jul 2018

Conference

Conference	11th FENS Forum of Neuroscience
Country/Territory	Germany
City	Berlin
Period	7/07/18 → 11/07/18

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Voss, T-D., Lewerenz, J., Appelt, F., Klaus, R., Hideyo, S., Albertini, G., Smolders, I., & Massie, A. (2018). C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo. In Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018

Voss, Timo-Daniel ; Lewerenz, Jan ; Appelt, Frederic ; Klaus, Richard ; Hideyo, Sato ; Albertini, Giulia ; Smolders, Ilse ; Massie, Ann. / C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo. Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018. 2018.

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title = "C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo",

abstract = "Inflammatory stimuli upregulate system xc- in vivo and in vitro. This is mediated by increased transcription of xCT, the specific subunit of system xc-. Counterintuitively, NFκB might rather represent an inhibitory feedback loop in the inflammatory induction of system xc-downstream of inflammatory pathways",

author = "Timo-Daniel Voss and Jan Lewerenz and Frederic Appelt and Richard Klaus and Sato Hideyo and Giulia Albertini and Ilse Smolders and Ann Massie",

year = "2018",

language = "English",

booktitle = "Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018",

note = "11th FENS Forum of Neuroscience ; Conference date: 07-07-2018 Through 11-07-2018",

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Voss, T-D, Lewerenz, J, Appelt, F, Klaus, R, Hideyo, S, Albertini, G, Smolders, I & Massie, A 2018, C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo. in Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018. 11th FENS Forum of Neuroscience, Berlin, Germany, 7/07/18.

C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo. / Voss, Timo-Daniel; Lewerenz, Jan; Appelt, Frederic; Klaus, Richard; Hideyo, Sato; Albertini, Giulia; Smolders, Ilse ; Massie, Ann.

Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018. 2018.

Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract (Book) › Research

TY - CHAP

T1 - C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo

AU - Voss, Timo-Daniel

AU - Lewerenz, Jan

AU - Appelt, Frederic

AU - Klaus, Richard

AU - Hideyo, Sato

AU - Albertini, Giulia

AU - Smolders, Ilse

AU - Massie, Ann

PY - 2018

Y1 - 2018

N2 - Inflammatory stimuli upregulate system xc- in vivo and in vitro. This is mediated by increased transcription of xCT, the specific subunit of system xc-. Counterintuitively, NFκB might rather represent an inhibitory feedback loop in the inflammatory induction of system xc-downstream of inflammatory pathways

AB - Inflammatory stimuli upregulate system xc- in vivo and in vitro. This is mediated by increased transcription of xCT, the specific subunit of system xc-. Counterintuitively, NFκB might rather represent an inhibitory feedback loop in the inflammatory induction of system xc-downstream of inflammatory pathways

UR - https://ep70.eventpilot.us/web/page.php?page=Session&project=FENS18&id=P_0000076740_0

M3 - Meeting abstract (Book)

BT - Federation of European Neuroscience Society, 11th FENS Forum of Neuroscience, Berlin, 7-11 july 2018

T2 - 11th FENS Forum of Neuroscience

Y2 - 7 July 2018 through 11 July 2018

ER -

C075 - Inflammatory signaling pathways up-regulate the cystine/glutamate antiporter system xc- in cortical murine astrocytes in vitro and in the brain in vivo

Abstract

Conference

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