Case study: Angiotensin receptor blockers (ARBs)

    Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review


    here is now also ample evidence that the "residence time" of a drug at it cellular target (such as a receptor or an enzyme) may affect its clinical performance. In this respect, a great deal of attention has been devoted to those situations in where optimal clinical performance requires continuing, high levels of target occupancy. This has for example been proposed to be the case with AT1 receptor antagonist candesartan.
    Original languageEnglish
    Title of host publicationKinetics and Thermodynamics of Drug binding
    EditorsKeserü G., Swinney D.
    Place of PublicationGermany
    Number of pages21
    ISBN (Print)978-3-527-33582-4
    Publication statusPublished - 2015

    Publication series

    NameWiley's Methods and Principles in Medicinal Chemistry Series

    Bibliographical note

    Keserü G. and Swinney D.


    • angiotensin receptors
    • radioligand binding
    • sartans
    • rebinding
    • binding kinetics


    Dive into the research topics of 'Case study: Angiotensin receptor blockers (ARBs)'. Together they form a unique fingerprint.

    Cite this