INTRODUCTION: Data regarding the efficacy of catheter ablation in patients with atrial fibrillation (AF) and patients' previous history of pulmonary lobectomy/pneumonectomy are scanty. We sought to evaluate the efficacy and long-term follow-up of catheter ablation in this highly selected group of patients.
MATERIAL AND METHODS: Twenty consecutive patients (8 females, 40%; median age 65.2 years old) with a history of pneumonectomy/lobectomy and paroxysmal or persistent AF, treated by means of pulmonary vein isolation (PVI) at ten participating centers were included. Procedural success, intra-procedural complications, and AF recurrences were considered.
RESULTS: Fifteen patients had a previous lobectomy and five patients had a complete pneumonectomy. A large proportion (65%) of PV stumps were electrically active and represented a source of firing in 20% of cases. PVI was performed by radiofrequency ablation in 13 patients (65%) and by cryoablation in the remaining 7 cases. Over a median follow up of 29.7 months, a total of 7 (33%) AF recurrences were recorded with neither a difference between patients treated with cryoablation or radiofrequency ablation or between the two genders.
CONCLUSIONS: Catheter ablation by radiofrequency ablation or cryoablation in patients with pulmonary stumps is feasible and safe. Long-term outcomes are favorable, and a similar efficacy of catheter ablation has been noticed in both males and females.
Bibliographical noteFunding Information:
Conflicts of Interest: A.A. is a consultant to Boston Scientific, Cairdac, Corvia, Microport CRM, EPD Philips, Radcliffe Publisher. He received speaker fees from Boston Scientific, Medtronic, and Microport, participates in clinical trials sponsored by Boston Scientific, Medtronic, EPD-Philips, and holds intellectual properties with Boston Scientific, Biosense Webster, and Microport CRM. G.C. has received a research grant (PZ00P3_180055) from the Swiss National Science Foundation (SNSF). S.B. is consultant for Medtronic, Boston Scientific, and Microport. L.M. Consultant and lecturer from Abbott, Biosense, Boston Scientific, Medtronic, Medlumics; Fellowship and research grants from Abbott, Biosense, Boston Scientific, Medtronic; Stockholder from Galgo Medical and Corify; C.K. is an occasional statistical consultant to Boston Scientific. All other co-authors do not any report conflict of interest.
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- atrial fibrillation
- pulmonary vein isolation
- pulmonary vein stump