Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection: Long-Term Results of an International Multicenter Study

Andrea Demarchi; Giulio Conte; Shih-Ann Chen; Li-Wei Lo; Wei-Tso Chen; Tom De Potter; Peter Geelen; Andrea Sarkozy; Francesco R Spera; Tobias Reichlin; Laurent Roten; Pascal Defaye; Adrien Carabelli; Serge Boveda; Hamed Bourenane; Lisa Riesinger; Simon Kochhäuser; Gala Caixal; Lluis Mont; Daniel Scherr; Martin Manninger; Francesco Pentimalli; Stefano Cornara; Catherine Klersy; Angelo Auricchio

doi:10.3390/jcm11061481

Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection: Long-Term Results of an International Multicenter Study

Andrea Demarchi, Giulio Conte, Shih-Ann Chen, Li-Wei Lo, Wei-Tso Chen, Tom De Potter, Peter Geelen, Andrea Sarkozy, Francesco R Spera, Tobias Reichlin, Laurent Roten, Pascal Defaye, Adrien Carabelli, Serge Boveda, Hamed Bourenane, Lisa Riesinger, Simon Kochhäuser, Gala Caixal, Lluis Mont, Daniel ScherrMartin Manninger, Francesco Pentimalli, Stefano Cornara, Catherine Klersy, Angelo Auricchio

Clinical sciences

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Abstract

INTRODUCTION: Data regarding the efficacy of catheter ablation in patients with atrial fibrillation (AF) and patients' previous history of pulmonary lobectomy/pneumonectomy are scanty. We sought to evaluate the efficacy and long-term follow-up of catheter ablation in this highly selected group of patients.

MATERIAL AND METHODS: Twenty consecutive patients (8 females, 40%; median age 65.2 years old) with a history of pneumonectomy/lobectomy and paroxysmal or persistent AF, treated by means of pulmonary vein isolation (PVI) at ten participating centers were included. Procedural success, intra-procedural complications, and AF recurrences were considered.

RESULTS: Fifteen patients had a previous lobectomy and five patients had a complete pneumonectomy. A large proportion (65%) of PV stumps were electrically active and represented a source of firing in 20% of cases. PVI was performed by radiofrequency ablation in 13 patients (65%) and by cryoablation in the remaining 7 cases. Over a median follow up of 29.7 months, a total of 7 (33%) AF recurrences were recorded with neither a difference between patients treated with cryoablation or radiofrequency ablation or between the two genders.

CONCLUSIONS: Catheter ablation by radiofrequency ablation or cryoablation in patients with pulmonary stumps is feasible and safe. Long-term outcomes are favorable, and a similar efficacy of catheter ablation has been noticed in both males and females.

Original language	English
Article number	1481
Number of pages	11
Journal	Journal of clinical medicine
Volume	11
Issue number	6
DOIs	https://doi.org/10.3390/jcm11061481
Publication status	Published - Mar 2022

Bibliographical note

Funding Information:
Conflicts of Interest: A.A. is a consultant to Boston Scientific, Cairdac, Corvia, Microport CRM, EPD Philips, Radcliffe Publisher. He received speaker fees from Boston Scientific, Medtronic, and Microport, participates in clinical trials sponsored by Boston Scientific, Medtronic, EPD-Philips, and holds intellectual properties with Boston Scientific, Biosense Webster, and Microport CRM. G.C. has received a research grant (PZ00P3_180055) from the Swiss National Science Foundation (SNSF). S.B. is consultant for Medtronic, Boston Scientific, and Microport. L.M. Consultant and lecturer from Abbott, Biosense, Boston Scientific, Medtronic, Medlumics; Fellowship and research grants from Abbott, Biosense, Boston Scientific, Medtronic; Stockholder from Galgo Medical and Corify; C.K. is an occasional statistical consultant to Boston Scientific. All other co-authors do not any report conflict of interest.

Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Copyright:
Copyright 2023 Elsevier B.V., All rights reserved.

Keywords

ablation
atrial fibrillation
follow-up
lobectomy
pneumonectomy
pulmonary vein isolation
pulmonary vein stump

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Demarchi, A., Conte, G., Chen, S-A., Lo, L-W., Chen, W-T., De Potter, T., Geelen, P., Sarkozy, A., Spera, F. R., Reichlin, T., Roten, L., Defaye, P., Carabelli, A., Boveda, S., Bourenane, H., Riesinger, L., Kochhäuser, S., Caixal, G., Mont, L., ... Auricchio, A. (2022). Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection: Long-Term Results of an International Multicenter Study. Journal of clinical medicine, 11(6), [1481]. https://doi.org/10.3390/jcm11061481

Demarchi, Andrea ; Conte, Giulio ; Chen, Shih-Ann ; Lo, Li-Wei ; Chen, Wei-Tso ; De Potter, Tom ; Geelen, Peter ; Sarkozy, Andrea ; Spera, Francesco R ; Reichlin, Tobias ; Roten, Laurent ; Defaye, Pascal ; Carabelli, Adrien ; Boveda, Serge ; Bourenane, Hamed ; Riesinger, Lisa ; Kochhäuser, Simon ; Caixal, Gala ; Mont, Lluis ; Scherr, Daniel ; Manninger, Martin ; Pentimalli, Francesco ; Cornara, Stefano ; Klersy, Catherine ; Auricchio, Angelo. / Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection : Long-Term Results of an International Multicenter Study. In: Journal of clinical medicine. 2022 ; Vol. 11, No. 6.

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title = "Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection: Long-Term Results of an International Multicenter Study",

abstract = "INTRODUCTION: Data regarding the efficacy of catheter ablation in patients with atrial fibrillation (AF) and patients' previous history of pulmonary lobectomy/pneumonectomy are scanty. We sought to evaluate the efficacy and long-term follow-up of catheter ablation in this highly selected group of patients.MATERIAL AND METHODS: Twenty consecutive patients (8 females, 40%; median age 65.2 years old) with a history of pneumonectomy/lobectomy and paroxysmal or persistent AF, treated by means of pulmonary vein isolation (PVI) at ten participating centers were included. Procedural success, intra-procedural complications, and AF recurrences were considered.RESULTS: Fifteen patients had a previous lobectomy and five patients had a complete pneumonectomy. A large proportion (65%) of PV stumps were electrically active and represented a source of firing in 20% of cases. PVI was performed by radiofrequency ablation in 13 patients (65%) and by cryoablation in the remaining 7 cases. Over a median follow up of 29.7 months, a total of 7 (33%) AF recurrences were recorded with neither a difference between patients treated with cryoablation or radiofrequency ablation or between the two genders.CONCLUSIONS: Catheter ablation by radiofrequency ablation or cryoablation in patients with pulmonary stumps is feasible and safe. Long-term outcomes are favorable, and a similar efficacy of catheter ablation has been noticed in both males and females.",

keywords = "ablation, atrial fibrillation, follow-up, lobectomy, pneumonectomy, pulmonary vein isolation, pulmonary vein stump",

author = "Andrea Demarchi and Giulio Conte and Shih-Ann Chen and Li-Wei Lo and Wei-Tso Chen and {De Potter}, Tom and Peter Geelen and Andrea Sarkozy and Spera, {Francesco R} and Tobias Reichlin and Laurent Roten and Pascal Defaye and Adrien Carabelli and Serge Boveda and Hamed Bourenane and Lisa Riesinger and Simon Kochh{\"a}user and Gala Caixal and Lluis Mont and Daniel Scherr and Martin Manninger and Francesco Pentimalli and Stefano Cornara and Catherine Klersy and Angelo Auricchio",

note = "Funding Information: Conflicts of Interest: A.A. is a consultant to Boston Scientific, Cairdac, Corvia, Microport CRM, EPD Philips, Radcliffe Publisher. He received speaker fees from Boston Scientific, Medtronic, and Microport, participates in clinical trials sponsored by Boston Scientific, Medtronic, EPD-Philips, and holds intellectual properties with Boston Scientific, Biosense Webster, and Microport CRM. G.C. has received a research grant (PZ00P3_180055) from the Swiss National Science Foundation (SNSF). S.B. is consultant for Medtronic, Boston Scientific, and Microport. L.M. Consultant and lecturer from Abbott, Biosense, Boston Scientific, Medtronic, Medlumics; Fellowship and research grants from Abbott, Biosense, Boston Scientific, Medtronic; Stockholder from Galgo Medical and Corify; C.K. is an occasional statistical consultant to Boston Scientific. All other co-authors do not any report conflict of interest. Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland. Copyright: Copyright 2023 Elsevier B.V., All rights reserved.",

year = "2022",

month = mar,

doi = "10.3390/jcm11061481",

language = "English",

volume = "11",

journal = "Journal of Clinical Medicine",

issn = "2077-0383",

publisher = "MDPI",

number = "6",

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Demarchi, A, Conte, G, Chen, S-A, Lo, L-W, Chen, W-T, De Potter, T, Geelen, P, Sarkozy, A, Spera, FR, Reichlin, T, Roten, L, Defaye, P, Carabelli, A, Boveda, S, Bourenane, H, Riesinger, L, Kochhäuser, S, Caixal, G, Mont, L, Scherr, D, Manninger, M, Pentimalli, F, Cornara, S, Klersy, C & Auricchio, A 2022, 'Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection: Long-Term Results of an International Multicenter Study', Journal of clinical medicine, vol. 11, no. 6, 1481. https://doi.org/10.3390/jcm11061481

Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection : Long-Term Results of an International Multicenter Study. / Demarchi, Andrea; Conte, Giulio; Chen, Shih-Ann; Lo, Li-Wei; Chen, Wei-Tso; De Potter, Tom; Geelen, Peter; Sarkozy, Andrea; Spera, Francesco R; Reichlin, Tobias; Roten, Laurent; Defaye, Pascal; Carabelli, Adrien; Boveda, Serge; Bourenane, Hamed; Riesinger, Lisa; Kochhäuser, Simon; Caixal, Gala; Mont, Lluis; Scherr, Daniel; Manninger, Martin; Pentimalli, Francesco; Cornara, Stefano; Klersy, Catherine; Auricchio, Angelo.

In: Journal of clinical medicine, Vol. 11, No. 6, 1481, 03.2022.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection

T2 - Long-Term Results of an International Multicenter Study

AU - Demarchi, Andrea

AU - Conte, Giulio

AU - Chen, Shih-Ann

AU - Lo, Li-Wei

AU - Chen, Wei-Tso

AU - De Potter, Tom

AU - Geelen, Peter

AU - Sarkozy, Andrea

AU - Spera, Francesco R

AU - Reichlin, Tobias

AU - Roten, Laurent

AU - Defaye, Pascal

AU - Carabelli, Adrien

AU - Boveda, Serge

AU - Bourenane, Hamed

AU - Riesinger, Lisa

AU - Kochhäuser, Simon

AU - Caixal, Gala

AU - Mont, Lluis

AU - Scherr, Daniel

AU - Manninger, Martin

AU - Pentimalli, Francesco

AU - Cornara, Stefano

AU - Klersy, Catherine

AU - Auricchio, Angelo

N1 - Funding Information: Conflicts of Interest: A.A. is a consultant to Boston Scientific, Cairdac, Corvia, Microport CRM, EPD Philips, Radcliffe Publisher. He received speaker fees from Boston Scientific, Medtronic, and Microport, participates in clinical trials sponsored by Boston Scientific, Medtronic, EPD-Philips, and holds intellectual properties with Boston Scientific, Biosense Webster, and Microport CRM. G.C. has received a research grant (PZ00P3_180055) from the Swiss National Science Foundation (SNSF). S.B. is consultant for Medtronic, Boston Scientific, and Microport. L.M. Consultant and lecturer from Abbott, Biosense, Boston Scientific, Medtronic, Medlumics; Fellowship and research grants from Abbott, Biosense, Boston Scientific, Medtronic; Stockholder from Galgo Medical and Corify; C.K. is an occasional statistical consultant to Boston Scientific. All other co-authors do not any report conflict of interest. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. Copyright: Copyright 2023 Elsevier B.V., All rights reserved.

PY - 2022/3

Y1 - 2022/3

N2 - INTRODUCTION: Data regarding the efficacy of catheter ablation in patients with atrial fibrillation (AF) and patients' previous history of pulmonary lobectomy/pneumonectomy are scanty. We sought to evaluate the efficacy and long-term follow-up of catheter ablation in this highly selected group of patients.MATERIAL AND METHODS: Twenty consecutive patients (8 females, 40%; median age 65.2 years old) with a history of pneumonectomy/lobectomy and paroxysmal or persistent AF, treated by means of pulmonary vein isolation (PVI) at ten participating centers were included. Procedural success, intra-procedural complications, and AF recurrences were considered.RESULTS: Fifteen patients had a previous lobectomy and five patients had a complete pneumonectomy. A large proportion (65%) of PV stumps were electrically active and represented a source of firing in 20% of cases. PVI was performed by radiofrequency ablation in 13 patients (65%) and by cryoablation in the remaining 7 cases. Over a median follow up of 29.7 months, a total of 7 (33%) AF recurrences were recorded with neither a difference between patients treated with cryoablation or radiofrequency ablation or between the two genders.CONCLUSIONS: Catheter ablation by radiofrequency ablation or cryoablation in patients with pulmonary stumps is feasible and safe. Long-term outcomes are favorable, and a similar efficacy of catheter ablation has been noticed in both males and females.

AB - INTRODUCTION: Data regarding the efficacy of catheter ablation in patients with atrial fibrillation (AF) and patients' previous history of pulmonary lobectomy/pneumonectomy are scanty. We sought to evaluate the efficacy and long-term follow-up of catheter ablation in this highly selected group of patients.MATERIAL AND METHODS: Twenty consecutive patients (8 females, 40%; median age 65.2 years old) with a history of pneumonectomy/lobectomy and paroxysmal or persistent AF, treated by means of pulmonary vein isolation (PVI) at ten participating centers were included. Procedural success, intra-procedural complications, and AF recurrences were considered.RESULTS: Fifteen patients had a previous lobectomy and five patients had a complete pneumonectomy. A large proportion (65%) of PV stumps were electrically active and represented a source of firing in 20% of cases. PVI was performed by radiofrequency ablation in 13 patients (65%) and by cryoablation in the remaining 7 cases. Over a median follow up of 29.7 months, a total of 7 (33%) AF recurrences were recorded with neither a difference between patients treated with cryoablation or radiofrequency ablation or between the two genders.CONCLUSIONS: Catheter ablation by radiofrequency ablation or cryoablation in patients with pulmonary stumps is feasible and safe. Long-term outcomes are favorable, and a similar efficacy of catheter ablation has been noticed in both males and females.

KW - ablation

KW - atrial fibrillation

KW - follow-up

KW - lobectomy

KW - pneumonectomy

KW - pulmonary vein isolation

KW - pulmonary vein stump

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U2 - 10.3390/jcm11061481

DO - 10.3390/jcm11061481

M3 - Article

C2 - 35329807

VL - 11

JO - Journal of Clinical Medicine

JF - Journal of Clinical Medicine

SN - 2077-0383

IS - 6

M1 - 1481

ER -

Catheter Ablation of Atrial Fibrillation in Patients with Previous Lobectomy or Partial Lung Resection: Long-Term Results of an International Multicenter Study

Abstract

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Keywords

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