Comment on "Some immunomodulatory effects of probiotic bacteria might be due to porcine neutrophil elastase inhibitor, a serpin present in MRS broth" [Immunol. Lett. (December) (in press) 1]

Benoît Foligné, Bruno Pot

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Serpins that are present in MRS broth were suspected to be responsible for some of the observed immunomodulatory effects of probiotic bacteria conditioned media. Some comments on this reporting, together with considerations dealing with manipulation of spent culture media and possible interfering effects, are discussed.

Original languageEnglish
Pages (from-to)227-228
Number of pages2
JournalImmunology Letters
Volume122
Issue number2
DOIs
Publication statusPublished - 21 Feb 2009

Keywords

  • Aerobiosis/immunology
  • Anaerobiosis/immunology
  • Animals
  • Culture Media, Conditioned/pharmacology
  • Fermentation/immunology
  • Immunologic Factors/metabolism
  • Probiotics/metabolism
  • Proteinase Inhibitory Proteins, Secretory/metabolism
  • Reactive Oxygen Species
  • Serpins/immunology
  • Swine
  • Tandem Mass Spectrometry

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