Abstract
The present invention relates to immunoglobulin single variable domains directed against human macrophage mannose receptor (MMR) and MMR-binding fragments thereof, and their use in non-invasive in vivo medical imaging for the detection, diagnosis and/or prognosis of cardiac sarcoidosis. Further provided are methods for diagnosis and/or prognosis of cardiac sarcoidosis, in particular by non-invasive in vivo medical imaging. Also provided are kits comprising such immunoglobulin single variable domains and fragments thereof for the production of a diagnostic for the detection of cardiac sarcoidosis.
| Original language | English |
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| Patent number | WO2022157373 |
| Publication status | Published - 2022 |