Projects per year
Abstract
Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function, these proteins are frequently involved in pathological processes. The present paper reviews the role of connexins and pannexins in liver toxicity and disease. As they act both as sensors and effectors in these in these deleterious events, connexins and pannexins could represent a set of novel clinical diagnostic biomarkers and drug targets.
Original language | English |
---|---|
Pages (from-to) | 177-186 |
Number of pages | 10 |
Journal | EXCLI Journal |
Volume | 15 |
Publication status | Published - 18 Feb 2016 |
Keywords
- Connexin
- Pannexin
- liver damage
Fingerprint
Dive into the research topics of 'Connexins and pannexins in liver damage'. Together they form a unique fingerprint.-
OZR2651: International Joint Research Group - Liver Connexin and Pannexin Research Group (LCPR)
Vinken, M., Rogiers, V., Cogliati, B. & Dagli, M. L.
1/08/14 → 1/07/26
Project: Fundamental
-
OZR2813: Bilaterale samenwerking ikv gemeenschappelijke doctoraatsproject: Bench Fee voor Joint PhD VUB-Universidade de Sao Paulo, Michael Maes
10/06/15 → 31/07/17
Project: Fundamental
Research output
- 23 Citations
- 8 Article
-
Connexin32: a mediator of acetaminophen-induced liver injury?
Maes, M., Mcgill, M. R., da Silva, T. C., Lebofsky, M., Monteiro de Araújo, C. M., Tiburcio, T., Alves Pereira, I. V., Willebrords, J., Crespo Yanguas, S., Farhood, A., Zaidan Dagli, M. L., Jaeschke, H., Cogliati, B. & Vinken, M., 1 May 2016, In: Toxicology Mechanism and Methods. 26, 2, p. 88-96 9 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Connexins, pannexins and their channels in fibroproliferative diseases
Cogliati, B., Mennecier, G., Willebrords, J., da Silva, T. C., Maes, M., Alves Pereira, I. V., Crespo Yanguas, S., Hernandez-Blazquez, F., Zaidan Dagli, M. L. & Vinken, M., 23 May 2016, In: Journal of Membrane Biology. 249, 3, p. 199-213Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
Involvement of connexin43 in acetaminophen-induced liver injury
Maes, M., Mcgill, M. R., da Silva, T. C., Abels, C., Lebofsky, M., Monteiro de Araújo, C. M., Tiburcio, T., Alves Pereira, I. V., Willebrords, J., Crespo Yanguas, S., Farhood, A., Beschin, A., Van Ginderachter, J., Zaidan Dagli, M. L., Jaeschke, H., Cogliati, B. & Vinken, M., 1 Jun 2016, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 6, p. 1111-1121 11 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus)
Activities
- 1 Talk or presentation at a workshop/seminar
-
The role of connexins, pannexins and their channels in liver fibrosis
Sara Crespo Yanguas (Speaker)
28 Nov 2018Activity: Talk or presentation › Talk or presentation at a workshop/seminar