CONTRAST-ENHANCED EXCIMER LASER CORONARY ANGIOPLASTY IN THE TREATMENT OF HEAVILY CALCIFIED LESIONS: A STEPWISE APPROACH

Rodolfo Caminiti; Giampaolo Vetta; Antonio Parlavecchio; Paolo Mazzone; Giuseppe Giacchi; Giorgio Sacchetta; Domenico Giovanni Della Rocca; Michele Magnocavallo; Vittorio Virga; Francesco Costa; Gianluca Di Bella; Scipione Carerj; Marco Contarini; Giampiero Vizzari; Antonio Micari

doi:10.1093/eurheartjsupp/suac121.305

CONTRAST-ENHANCED EXCIMER LASER CORONARY ANGIOPLASTY IN THE TREATMENT OF HEAVILY CALCIFIED LESIONS: A STEPWISE APPROACH

Rodolfo Caminiti, Giampaolo Vetta, Antonio Parlavecchio, Paolo Mazzone, Giuseppe Giacchi, Giorgio Sacchetta, Domenico Giovanni Della Rocca, Michele Magnocavallo, Vittorio Virga, Francesco Costa, Gianluca Di Bella, Scipione Carerj, Marco Contarini, Giampiero Vizzari, Antonio Micari

Research output: Contribution to journal › Article › peer-review

Abstract

Introduction: The treatment of heavily calcified lesions is a challenge for the interventional cardiologist. The Excimer laser coronary atherectomy (ELCA) is a plaque modification tool and the main mechanism of action seems to be the photomechanical delivering acoustic pressure with a mechanical disruption of the plaque in front of the catheter tip. Objective: To evaluate the effectiveness of the contrast-enhanced ELCA by a stepwise approach, with incremental frequency/fluency in the treatment of calcified lesions in different contexts. Methods: We retrospectively enrolled consecutively all patients undergoing contrast-enhanced ELCA-assisted PCIs between 2018 and 2021 at the Cardiology Unit of “Umberto I” Hospital of Syracuse (Italy). The frequency/fluency ELCA profile used with a stepwise approach were 50/50, 60/60, 70/70 and 80/80. ELCA technical success was defined as the laser catheter crossing the entire length of the target lesion established by angiographic evidence of the catheter tip in the artery distal to the stenosis. Procedural success was defined as

Original language	English
Number of pages	1
Journal	European Heart Journal Supplements
Volume	24
DOIs	https://doi.org/10.1093/eurheartjsupp/suac121.305
Publication status	Published - 1 Dec 2022

Keywords

acute coronary syndrome
adult
catheter
conference abstract
contrast enhancement
coronary atherectomy
coronary care unit
excimer laser
female
heart arrhythmia
heart infarction
hospital discharge
human
left anterior descending coronary artery
major adverse cardiac event
major clinical study
male
restenosis
retrospective study
right coronary artery
surgery
target lesion revascularization
transluminal coronary angioplasty

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Caminiti, R., Vetta, G., Parlavecchio, A., Mazzone, P., Giacchi, G., Sacchetta, G., Della Rocca, D. G., Magnocavallo, M., Virga, V., Costa, F., Di Bella, G., Carerj, S., Contarini, M., Vizzari, G., & Micari, A. (2022). CONTRAST-ENHANCED EXCIMER LASER CORONARY ANGIOPLASTY IN THE TREATMENT OF HEAVILY CALCIFIED LESIONS: A STEPWISE APPROACH. European Heart Journal Supplements, 24. https://doi.org/10.1093/eurheartjsupp/suac121.305

@article{f9a92124b44c4d0a81a96a0de04820e1,

title = "CONTRAST-ENHANCED EXCIMER LASER CORONARY ANGIOPLASTY IN THE TREATMENT OF HEAVILY CALCIFIED LESIONS: A STEPWISE APPROACH",

abstract = "Introduction: The treatment of heavily calcified lesions is a challenge for the interventional cardiologist. The Excimer laser coronary atherectomy (ELCA) is a plaque modification tool and the main mechanism of action seems to be the photomechanical delivering acoustic pressure with a mechanical disruption of the plaque in front of the catheter tip. Objective: To evaluate the effectiveness of the contrast-enhanced ELCA by a stepwise approach, with incremental frequency/fluency in the treatment of calcified lesions in different contexts. Methods: We retrospectively enrolled consecutively all patients undergoing contrast-enhanced ELCA-assisted PCIs between 2018 and 2021 at the Cardiology Unit of “Umberto I” Hospital of Syracuse (Italy). The frequency/fluency ELCA profile used with a stepwise approach were 50/50, 60/60, 70/70 and 80/80. ELCA technical success was defined as the laser catheter crossing the entire length of the target lesion established by angiographic evidence of the catheter tip in the artery distal to the stenosis. Procedural success was defined as",

keywords = "acute coronary syndrome, adult, catheter, conference abstract, contrast enhancement, coronary atherectomy, coronary care unit, excimer laser, female, heart arrhythmia, heart infarction, hospital discharge, human, left anterior descending coronary artery, major adverse cardiac event, major clinical study, male, restenosis, retrospective study, right coronary artery, surgery, target lesion revascularization, transluminal coronary angioplasty",

author = "Rodolfo Caminiti and Giampaolo Vetta and Antonio Parlavecchio and Paolo Mazzone and Giuseppe Giacchi and Giorgio Sacchetta and {Della Rocca}, {Domenico Giovanni} and Michele Magnocavallo and Vittorio Virga and Francesco Costa and {Di Bella}, Gianluca and Scipione Carerj and Marco Contarini and Giampiero Vizzari and Antonio Micari",

year = "2022",

month = dec,

day = "1",

doi = "10.1093/eurheartjsupp/suac121.305",

language = "English",

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journal = "European Heart Journal Supplements",

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Caminiti, R, Vetta, G, Parlavecchio, A, Mazzone, P, Giacchi, G, Sacchetta, G, Della Rocca, DG, Magnocavallo, M, Virga, V, Costa, F, Di Bella, G, Carerj, S, Contarini, M, Vizzari, G & Micari, A 2022, 'CONTRAST-ENHANCED EXCIMER LASER CORONARY ANGIOPLASTY IN THE TREATMENT OF HEAVILY CALCIFIED LESIONS: A STEPWISE APPROACH', European Heart Journal Supplements, vol. 24. https://doi.org/10.1093/eurheartjsupp/suac121.305

TY - JOUR

T1 - CONTRAST-ENHANCED EXCIMER LASER CORONARY ANGIOPLASTY IN THE TREATMENT OF HEAVILY CALCIFIED LESIONS: A STEPWISE APPROACH

AU - Caminiti, Rodolfo

AU - Vetta, Giampaolo

AU - Parlavecchio, Antonio

AU - Mazzone, Paolo

AU - Giacchi, Giuseppe

AU - Sacchetta, Giorgio

AU - Della Rocca, Domenico Giovanni

AU - Magnocavallo, Michele

AU - Virga, Vittorio

AU - Costa, Francesco

AU - Di Bella, Gianluca

AU - Carerj, Scipione

AU - Contarini, Marco

AU - Vizzari, Giampiero

AU - Micari, Antonio

PY - 2022/12/1

Y1 - 2022/12/1

N2 - Introduction: The treatment of heavily calcified lesions is a challenge for the interventional cardiologist. The Excimer laser coronary atherectomy (ELCA) is a plaque modification tool and the main mechanism of action seems to be the photomechanical delivering acoustic pressure with a mechanical disruption of the plaque in front of the catheter tip. Objective: To evaluate the effectiveness of the contrast-enhanced ELCA by a stepwise approach, with incremental frequency/fluency in the treatment of calcified lesions in different contexts. Methods: We retrospectively enrolled consecutively all patients undergoing contrast-enhanced ELCA-assisted PCIs between 2018 and 2021 at the Cardiology Unit of “Umberto I” Hospital of Syracuse (Italy). The frequency/fluency ELCA profile used with a stepwise approach were 50/50, 60/60, 70/70 and 80/80. ELCA technical success was defined as the laser catheter crossing the entire length of the target lesion established by angiographic evidence of the catheter tip in the artery distal to the stenosis. Procedural success was defined as

AB - Introduction: The treatment of heavily calcified lesions is a challenge for the interventional cardiologist. The Excimer laser coronary atherectomy (ELCA) is a plaque modification tool and the main mechanism of action seems to be the photomechanical delivering acoustic pressure with a mechanical disruption of the plaque in front of the catheter tip. Objective: To evaluate the effectiveness of the contrast-enhanced ELCA by a stepwise approach, with incremental frequency/fluency in the treatment of calcified lesions in different contexts. Methods: We retrospectively enrolled consecutively all patients undergoing contrast-enhanced ELCA-assisted PCIs between 2018 and 2021 at the Cardiology Unit of “Umberto I” Hospital of Syracuse (Italy). The frequency/fluency ELCA profile used with a stepwise approach were 50/50, 60/60, 70/70 and 80/80. ELCA technical success was defined as the laser catheter crossing the entire length of the target lesion established by angiographic evidence of the catheter tip in the artery distal to the stenosis. Procedural success was defined as

KW - acute coronary syndrome

KW - adult

KW - catheter

KW - conference abstract

KW - contrast enhancement

KW - coronary atherectomy

KW - coronary care unit

KW - excimer laser

KW - female

KW - heart arrhythmia

KW - heart infarction

KW - hospital discharge

KW - human

KW - left anterior descending coronary artery

KW - major adverse cardiac event

KW - major clinical study

KW - male

KW - restenosis

KW - retrospective study

KW - right coronary artery

KW - surgery

KW - target lesion revascularization

KW - transluminal coronary angioplasty

U2 - 10.1093/eurheartjsupp/suac121.305

DO - 10.1093/eurheartjsupp/suac121.305

M3 - Article

SN - 1520-765X

VL - 24

JO - European Heart Journal Supplements

JF - European Heart Journal Supplements

ER -

CONTRAST-ENHANCED EXCIMER LASER CORONARY ANGIOPLASTY IN THE TREATMENT OF HEAVILY CALCIFIED LESIONS: A STEPWISE APPROACH

Abstract

Keywords

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