Corneal Neurotization—Indications, Surgical Techniques and Outcomes

Diana Carmen Dragnea, Iva Krolo, Carina Koppen, Callum Faris, Bert Van den Bogerd, Sorcha Ní Dhubhghaill

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Corneal neurotization is a promising surgical approach for the treatment of moderate to severe neurotrophic keratopathy. This technique aims to restore corneal sensation by transferring healthy nerves, either directly or via a conduit, to the anesthetic cornea. This review provides a report on the current state of development, evidence, and experience in the field. We summarize the data available from clinical reports and case series, placing an emphasis on the diversity of the surgical techniques reported. While these data are encouraging, they also highlight the need for a consensus in reporting outcomes and highlight how the next step will involve validating putative outcome parameters when researching and reporting corneal neurotization surgery.
Original languageEnglish
Article number2214
Pages (from-to)1-22
Number of pages22
JournalJournal of clinical medicine
Issue number6
Publication statusPublished - Mar 2023

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