Coronary microvascular dysfunction: Phenotype-specific targeted therapies

Gianluca Mincione; Matteo Maurina; Alice Benedetti; Mauro Chiarito; Giulio G Stefanini; Pieter C Smits; Valeria Paradies

doi:10.1016/j.carrev.2025.06.014

Coronary microvascular dysfunction: Phenotype-specific targeted therapies

Gianluca Mincione, Matteo Maurina, Alice Benedetti, Mauro Chiarito, Giulio G Stefanini, Pieter C Smits, Valeria Paradies

Research output: Contribution to journal › Article › peer-review

Abstract

Coronary microvascular dysfunction has always been a clinical entity that is often underdiagnosed and with limited therapeutic options. In this review, we aim to provide a comprehensive view of the pathology, correlating it with specific syndromic presentations to which it is often linked, and based on these, propose tailored diagnostic and therapeutic strategies.

Original language	English
Pages (from-to)	30-34
Number of pages	5
Journal	Cardiovascular Revascularization Medicine
Volume	76
DOIs	https://doi.org/10.1016/j.carrev.2025.06.014
Publication status	Published - Jul 2025

Bibliographical note

Keywords

Humans
Microcirculation/drug effects
Phenotype
Coronary Circulation/drug effects
Coronary Vessels/physiopathology
Coronary Artery Disease/physiopathology
Microvessels/physiopathology
Prognosis
Predictive Value of Tests
Risk Factors

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title = "Coronary microvascular dysfunction: Phenotype-specific targeted therapies",

abstract = "Coronary microvascular dysfunction has always been a clinical entity that is often underdiagnosed and with limited therapeutic options. In this review, we aim to provide a comprehensive view of the pathology, correlating it with specific syndromic presentations to which it is often linked, and based on these, propose tailored diagnostic and therapeutic strategies.",

keywords = "Humans, Microcirculation/drug effects, Phenotype, Coronary Circulation/drug effects, Coronary Vessels/physiopathology, Coronary Artery Disease/physiopathology, Microvessels/physiopathology, Prognosis, Predictive Value of Tests, Risk Factors",

author = "Gianluca Mincione and Matteo Maurina and Alice Benedetti and Mauro Chiarito and Stefanini, {Giulio G} and Smits, {Pieter C} and Valeria Paradies",

year = "2025",

month = jul,

doi = "10.1016/j.carrev.2025.06.014",

language = "English",

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T2 - Phenotype-specific targeted therapies

AU - Mincione, Gianluca

AU - Maurina, Matteo

AU - Benedetti, Alice

AU - Chiarito, Mauro

AU - Stefanini, Giulio G

AU - Smits, Pieter C

AU - Paradies, Valeria

PY - 2025/7

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N2 - Coronary microvascular dysfunction has always been a clinical entity that is often underdiagnosed and with limited therapeutic options. In this review, we aim to provide a comprehensive view of the pathology, correlating it with specific syndromic presentations to which it is often linked, and based on these, propose tailored diagnostic and therapeutic strategies.

AB - Coronary microvascular dysfunction has always been a clinical entity that is often underdiagnosed and with limited therapeutic options. In this review, we aim to provide a comprehensive view of the pathology, correlating it with specific syndromic presentations to which it is often linked, and based on these, propose tailored diagnostic and therapeutic strategies.

KW - Humans

KW - Microcirculation/drug effects

KW - Phenotype

KW - Coronary Circulation/drug effects

KW - Coronary Vessels/physiopathology

KW - Coronary Artery Disease/physiopathology

KW - Microvessels/physiopathology

KW - Prognosis

KW - Predictive Value of Tests

KW - Risk Factors

UR - http://www.scopus.com/inward/record.url?scp=105008549266&partnerID=8YFLogxK

U2 - 10.1016/j.carrev.2025.06.014

DO - 10.1016/j.carrev.2025.06.014

M3 - Article

C2 - 40544126

SN - 1553-8389

VL - 76

SP - 30

EP - 34

JO - Cardiovascular Revascularization Medicine

JF - Cardiovascular Revascularization Medicine

ER -

Coronary microvascular dysfunction: Phenotype-specific targeted therapies

Abstract

Bibliographical note

Keywords

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