Cost/benefit of synbiotics in acute infectious gastroenteritis : spend to save

Yvan Vandenplas, S. De Hert

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

The cost/benefit ratio of probiotics in the ambulatory treatment of acute infectious gastro-enteritis with or without a synbiotic food supplement (containing fructo-oligosaccharides and probiotic strains of Streptoccoccus thermophilus, Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium lactis and Bifidobacterium infantis) has been studied. 111 children (median age 37 and 43 months for the synbiotic and placebo group, respectively) with acute infectious gastroenteritis were included in a randomised, prospective placebo-controlled trial performed in primary health care. All children were treated with an oral rehydration solution and with the synbiotic food supplement (n=57) or placebo (n=54). Physicians were allowed to prescribe additional medication according to what they considered as 'necessary'. Cost of add-on medication and total healthcare cost were calculated. Median duration of diarrhoea was 1 day shorter (95% confidence interval -0.6 to -1.9 days) in the symbiotic than in the placebo group (P
Original languageEnglish
Pages (from-to)189-194
Number of pages6
JournalBenef Microbes
Volume1
Publication statusPublished - 1 Sep 2012

Keywords

  • acute infectious gastroenteritis

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