Effective cerebello-cerebral connectivity during implicit and explicit social belief sequence learning using dynamic causal modeling

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)
22 Downloads (Pure)

Abstract

To study social sequence learning, earlier functional magnetic resonance imaging (fMRI) studies investigated the neural correlates of a novel Belief Serial Reaction Time task in which participants learned sequences of beliefs held by protagonists. The results demonstrated the involvement of the mentalizing network in the posterior cerebellum and cerebral areas (e.g. temporoparietal junction, precuneus and temporal pole) during implicit and explicit social sequence learning. However, little is known about the neural functional interaction between these areas during this task. Dynamic causal modeling analyses for both implicit and explicit belief sequence learning revealed that the posterior cerebellar Crus I & II were effectively connected to cerebral mentalizing areas, especially the bilateral temporoparietal junction, via closed loops (i.e. bidirectional functional connections that initiate and terminate at the same cerebellar and cerebral areas). There were more closed loops during implicit than explicit learning, which may indicate that the posterior cerebellum may be more involved in implicitly learning sequential social information. Our analysis supports the general view that the posterior cerebellum receives incoming signals from critical mentalizing areas in the cerebrum to identify sequences of social actions and then sends signals back to the same cortical mentalizing areas to better prepare for others' social actions and one's responses to it.

Original languageEnglish
Article numbernsac044
Number of pages15
JournalSocial Cognitive and Affective Neuroscience
Volume18
Issue number1
Early online date7 Jul 2022
DOIs
Publication statusPublished - 9 Jan 2023

Bibliographical note

Funding Information:
This research was funded by Strategic Research Program (SRP)57 awarded by the Vrije Universiteit Brussel to Frank Van Overwalle and a China Scholarship Council (CSC) fellowship awarded to Qianying Ma.

Publisher Copyright:
© The Author(s) 2023. Published by Oxford University Press.

Copyright:
Copyright 2023 Elsevier B.V., All rights reserved.

Keywords

  • cerebellum
  • dynamic causal modelling
  • false belief
  • serial reaction time task
  • social cognition

Fingerprint

Dive into the research topics of 'Effective cerebello-cerebral connectivity during implicit and explicit social belief sequence learning using dynamic causal modeling'. Together they form a unique fingerprint.

Cite this