EFFECTS OF A SHORT EXPOSURE TO MULTIDIRECTIONAL VIBRATIONS (ANDULLATION®) ON LYMPHATIC SYSTEM AND SKIN MICROCIRCULATION IN MICE

Frederic Pastouret, Lucia Cardozo, Pierre Lievens

Research output: Contribution to journalMeeting abstract (Journal)

Abstract

Introduction: Physiological effects of Whole Body Vibration are intensively studied in medical fields.
Objective: To examine the short time effects of multidirectional vibrations (delivered in horizontal position) on the lymph node dye
accumulation and skin microcirculation in mice.
Methods: Part 1: Mice were randomly allocated to three groups: Whole Body Vibrations (30 Hz, 3 minutes) (N= 15); manual massage
(3 minutes) (N = 15) and a control group (N= 10). Interventions were applied after 20 µl footpad injections of Evans blue dye (EBD).
Dye quantity determination (µg) in the popliteal nodes was assessed by spectrophotometry (620 nm).
Part 2: Different periods of vibrations (3, 6 and 10 minutes, 30Hz) were locally delivered in a horizontal position on the abdominal skin
in 3 randomized groups of mice (N = 42). All groups were compared to a control group (N = 14). The ‘in vivo’ measuring of the
arterial and venous diameters was done before and after each vibration period.
Results: Part 1: After vibrations, the quantity (mean±sd) of EBD in popliteal nodes was found higher in the WBV mice than in the
control or massage groups (respectively, 0.56 ±0.26, 0.14±0.17, p˂0.05, 0.22±0.16, p˂0.05).
Part 2: Average venous diameters after 6 to 10 minutes of vibrations were significantly increased (7 and 12%, p-values 0.026 and
0.013), while 3 minutes did not significantly influence average venous diameters. Arterial diameters did not significantly vary after 3,
6 and 10 minutes. As for the placebo group, variations of arterial and venous diameters during 10 minutes were not significant.
Conclusions: Lymph node dye accumulation is better after a short vibrations exposure than without intervention or with injection site
massage.
Vasodilatory effect of low frequency vibrations was demonstrated. An endothelium “shear stress” induced by “skin massage” is
retained as hypothesis and generates local venous vasodilation and local subcutaneous blood flow increase.
Original languageEnglish
Pages (from-to)63-63
Number of pages1
JournalThe European Journal of Lymphology and Related Problems
Volume28
Issue number74
Publication statusPublished - 2016
Event42th European Society of Lymphology Congress - Institut de Formation aux Metiers de la Santé, GHR Mulhouse et Sud Alsace, 2 rue du Dr Leon Mangeney, Mulhouse, France
Duration: 13 May 201614 May 2016

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